"Polycomb-Group Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of proteins that play a role in CHROMATIN REMODELING. They are best known for silencing HOX GENES and the regulation of EPIGENETIC PROCESSES.
| Descriptor ID |
D063146
|
| MeSH Number(s) |
D05.500.781 D12.776.660.235.600 D12.776.664.235.800 D12.776.930.780.890
|
| Concept/Terms |
Polycomb-Group Proteins- Polycomb-Group Proteins
- Polycomb Group Proteins
- Polycomb Repressive Complex Proteins
- PcG Complex Proteins
Polycomb-Group Protein Complexes- Polycomb-Group Protein Complexes
- Complexes, Polycomb-Group Protein
- Polycomb Group Protein Complexes
- Protein Complexes, Polycomb-Group
|
Below are MeSH descriptors whose meaning is more general than "Polycomb-Group Proteins".
Below are MeSH descriptors whose meaning is more specific than "Polycomb-Group Proteins".
This graph shows the total number of publications written about "Polycomb-Group Proteins" by people in this website by year, and whether "Polycomb-Group Proteins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2008 | 0 | 2 | 2 |
| 2010 | 0 | 2 | 2 |
| 2011 | 0 | 1 | 1 |
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Below are the most recent publications written about "Polycomb-Group Proteins" by people in Profiles.
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Gong Y, Huo L, Liu P, Sneige N, Sun X, Ueno NT, Lucci A, Buchholz TA, Valero V, Cristofanilli M. Polycomb group protein EZH2 is frequently expressed in inflammatory breast cancer and is predictive of worse clinical outcome. Cancer. 2011 Dec 15; 117(24):5476-84.
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Zhao J, Ohsumi TK, Kung JT, Ogawa Y, Grau DJ, Sarma K, Song JJ, Kingston RE, Borowsky M, Lee JT. Genome-wide identification of polycomb-associated RNAs by RIP-seq. Mol Cell. 2010 Dec 22; 40(6):939-53.
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Wilkinson F, Pratt H, Atchison ML. PcG recruitment by the YY1 REPO domain can be mediated by Yaf2. J Cell Biochem. 2010 Feb 15; 109(3):478-86.
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Fujioka M, Yusibova GL, Zhou J, Jaynes JB. The DNA-binding Polycomb-group protein Pleiohomeotic maintains both active and repressed transcriptional states through a single site. Development. 2008 Dec; 135(24):4131-9.
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Zhang XY, Pfeiffer HK, Thorne AW, McMahon SB. USP22, an hSAGA subunit and potential cancer stem cell marker, reverses the polycomb-catalyzed ubiquitylation of histone H2A. Cell Cycle. 2008 Jun 1; 7(11):1522-4.
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Hwang C, Giri VN, Wilkinson JC, Wright CW, Wilkinson AS, Cooney KA, Duckett CS. EZH2 regulates the transcription of estrogen-responsive genes through association with REA, an estrogen receptor corepressor. Breast Cancer Res Treat. 2008 Jan; 107(2):235-42.
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Atchison L, Ghias A, Wilkinson F, Bonini N, Atchison ML. Transcription factor YY1 functions as a PcG protein in vivo. EMBO J. 2003 Mar 17; 22(6):1347-58.
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Rebbeck TR, Walker AH, Zeigler-Johnson C, Weisburg S, Martin AM, Nathanson KL, Wein AJ, Malkowicz SB. Association of HPC2/ELAC2 genotypes and prostate cancer. Am J Hum Genet. 2000 Oct; 67(4):1014-9.