"Polycomb-Group Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of proteins that play a role in CHROMATIN REMODELING. They are best known for silencing HOX GENES and the regulation of EPIGENETIC PROCESSES.
| Descriptor ID |
D063146
|
| MeSH Number(s) |
D05.500.781 D12.776.660.235.600 D12.776.664.235.800 D12.776.930.780.890
|
| Concept/Terms |
Polycomb-Group Proteins- Polycomb-Group Proteins
- Polycomb Group Proteins
- Polycomb Repressive Complex Proteins
- PcG Complex Proteins
Polycomb-Group Protein Complexes- Polycomb-Group Protein Complexes
- Complexes, Polycomb-Group Protein
- Polycomb Group Protein Complexes
- Protein Complexes, Polycomb-Group
|
Below are MeSH descriptors whose meaning is more general than "Polycomb-Group Proteins".
Below are MeSH descriptors whose meaning is more specific than "Polycomb-Group Proteins".
This graph shows the total number of publications written about "Polycomb-Group Proteins" by people in this website by year, and whether "Polycomb-Group Proteins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 |
| 2008 | 0 | 2 | 2 |
| 2010 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2013 | 1 | 1 | 2 |
| 2025 | 1 | 0 | 1 |
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Below are the most recent publications written about "Polycomb-Group Proteins" by people in Profiles.
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Wei S, Patchefsky AS, Pei J, Brown SA, Basu Mallick A, Wang Z, Jiang W. PHF1::TFE3-positive fibromyxoid sarcoma? Report of 2 cases and review of 13 cases of PHF1::TFE3-positive ossifying fibromyxoid tumor in the literature. Am J Clin Pathol. 2025 02 12; 163(2):224-230.
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Fujioka M, Sun G, Jaynes JB. The Drosophila eve insulator Homie promotes eve expression and protects the adjacent gene from repression by polycomb spreading. PLoS Genet. 2013 Oct; 9(10):e1003883.
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Petruk S, Black KL, Kovermann SK, Brock HW, Mazo A. Stepwise histone modifications are mediated by multiple enzymes that rapidly associate with nascent DNA during replication. Nat Commun. 2013; 4:2841.
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Gong Y, Huo L, Liu P, Sneige N, Sun X, Ueno NT, Lucci A, Buchholz TA, Valero V, Cristofanilli M. Polycomb group protein EZH2 is frequently expressed in inflammatory breast cancer and is predictive of worse clinical outcome. Cancer. 2011 Dec 15; 117(24):5476-84.
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Zhao J, Ohsumi TK, Kung JT, Ogawa Y, Grau DJ, Sarma K, Song JJ, Kingston RE, Borowsky M, Lee JT. Genome-wide identification of polycomb-associated RNAs by RIP-seq. Mol Cell. 2010 Dec 22; 40(6):939-53.
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Fujioka M, Yusibova GL, Zhou J, Jaynes JB. The DNA-binding Polycomb-group protein Pleiohomeotic maintains both active and repressed transcriptional states through a single site. Development. 2008 Dec; 135(24):4131-9.
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Zhang XY, Pfeiffer HK, Thorne AW, McMahon SB. USP22, an hSAGA subunit and potential cancer stem cell marker, reverses the polycomb-catalyzed ubiquitylation of histone H2A. Cell Cycle. 2008 Jun 01; 7(11):1522-4.
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Rebbeck TR, Walker AH, Zeigler-Johnson C, Weisburg S, Martin AM, Nathanson KL, Wein AJ, Malkowicz SB. Association of HPC2/ELAC2 genotypes and prostate cancer. Am J Hum Genet. 2000 Oct; 67(4):1014-9.