Receptors, Metabotropic Glutamate

"Receptors, Metabotropic Glutamate" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Cell surface proteins that bind glutamate and act through G-proteins to influence second messenger systems. Several types of metabotropic glutamate receptors have been cloned. They differ in pharmacology, distribution, and mechanisms of action.

Descriptor ID	D018094
MeSH Number(s)	D12.776.543.750.695.450 D12.776.543.750.720.200.450.500
Concept/Terms	Receptors, Metabotropic Glutamate Receptors, Metabotropic Glutamate Metabotropic Glutamate Receptor Glutamate Receptor, Metabotropic Receptor, Metabotropic Glutamate Metabotropic Glutamate Receptors Receptors, Glutamate, Metabotropic Glutamate Receptors, Metabotropic

Below are MeSH descriptors whose meaning is more general than "Receptors, Metabotropic Glutamate".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Membrane Proteins [D12.776.543]
Receptors, Cell Surface [D12.776.543.750]
Receptors, G-Protein-Coupled [D12.776.543.750.695]
Receptors, Metabotropic Glutamate [D12.776.543.750.695.450]
Receptors, Neurotransmitter [D12.776.543.750.720]
Receptors, Amino Acid [D12.776.543.750.720.200]
Receptors, Glutamate [D12.776.543.750.720.200.450]
Receptors, Metabotropic Glutamate [D12.776.543.750.720.200.450.500]

Below are MeSH descriptors whose meaning is related to "Receptors, Metabotropic Glutamate".

Below are MeSH descriptors whose meaning is more specific than "Receptors, Metabotropic Glutamate".

Receptors, Metabotropic Glutamate
Receptor, Metabotropic Glutamate 5

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Receptors, Metabotropic Glutamate" by people in this website by year, and whether "Receptors, Metabotropic Glutamate" was a major or minor topic of these publications.

Bar chart showing 14 publications over 12 distinct years, with a maximum of 2 publications in 2016 and 2023

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2002	0	1	1
2004	1	0	1
2008	1	0	1
2009	1	0	1
2010	0	1	1
2011	0	1	1
2012	0	1	1
2014	1	0	1
2015	0	1	1
2016	2	0	2
2018	1	0	1
2023	2	0	2

Below are the most recent publications written about "Receptors, Metabotropic Glutamate" by people in Profiles.

De Gasperi R, Gama Sosa MA, Perez Garcia G, Perez GM, Pryor D, Morrison CL, Lind R, Abutarboush R, Kawoos U, Statz JK, Patterson J, Hof PR, Zhu CW, Ahlers ST, Cook DG, Elder GA. Metabotropic Glutamate Receptor 2 Expression Is Chronically Elevated in Male Rats With Post-Traumatic Stress Disorder Related Behavioral Traits Following Repetitive Low-Level Blast Exposure. J Neurotrauma. 2024 03; 41(5-6):714-733.

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Inami S, Afonso DJS, Koh K. Sleep problems in old age: metabotropic glutamate receptor to the rescue. Sleep. 2023 05 10; 46(5).

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Elia J, Ungal G, Kao C, Ambrosini A, De Jesus-Rosario N, Larsen L, Chiavacci R, Wang T, Kurian C, Titchen K, Sykes B, Hwang S, Kumar B, Potts J, Davis J, Malatack J, Slattery E, Moorthy G, Zuppa A, Weller A, Byrne E, Li YR, Kraft WK, Hakonarson H. Fasoracetam in adolescents with ADHD and glutamatergic gene network variants disrupting mGluR neurotransmitter signaling. Nat Commun. 2018 01 16; 9(1):4.

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Cheng G, Werner TJ, Newberg A, Alavi A. Failed PET Application Attempts in the Past, Can We Avoid Them in the Future? Mol Imaging Biol. 2016 12; 18(6):797-802.

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Friedman LK, Sharma A, Corcia M, Webster T, Qazi L, Simsovits D, Khalil Y, Hu S, Kantrowitz M, Hong H. Selective inhibition of metabotropic glutamate type 1 alpha receptor (mGluR1a) reduces cell proliferation and migration following status epilepticus in early development. Int J Dev Neurosci. 2016 Nov; 54:6-21.

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Lakkaraju SK, Yu W, Raman EP, Hershfeld AV, Fang L, Deshpande DA, MacKerell AD. Mapping functional group free energy patterns at protein occluded sites: nuclear receptors and G-protein coupled receptors. J Chem Inf Model. 2015 Mar 23; 55(3):700-8.

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Teh JL, Shah R, Shin SS, Wen Y, Mehnert JM, Goydos J, Chen S. Metabotropic glutamate receptor 1 mediates melanocyte transformation via transactivation of insulin-like growth factor 1 receptor. Pigment Cell Melanoma Res. 2014 Jul; 27(4):621-9.

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Teh JL, Chen S. Glutamatergic signaling in cellular transformation. Pigment Cell Melanoma Res. 2012 May; 25(3):331-42.

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Eisenman LM. Ethanol and vestibular stimulation reveal simple and complex aspects of cerebellar heterogeneity. Cerebellum. 2011 Sep; 10(3):475-83.

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McBride SM, Choi CH, Schoenfeld BP, Bell AJ, Liebelt DA, Ferreiro D, Choi RJ, Hinchey P, Kollaros M, Terlizzi AM, Ferrick NJ, Koenigsberg E, Rudominer RL, Sumida A, Chiorean S, Siwicki KK, Nguyen HT, Fortini ME, McDonald TV, Jongens TA. Pharmacological and genetic reversal of age-dependent cognitive deficits attributable to decreased presenilin function. J Neurosci. 2010 Jul 14; 30(28):9510-22.

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