"Receptors, Muscarinic" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
One of the two major classes of cholinergic receptors. Muscarinic receptors were originally defined by their preference for MUSCARINE over NICOTINE. There are several subtypes (usually M1, M2, M3....) that are characterized by their cellular actions, pharmacology, and molecular biology.
| Descriptor ID |
D011976
|
| MeSH Number(s) |
D12.776.543.750.695.475 D12.776.543.750.720.360.500
|
| Concept/Terms |
Receptors, Muscarinic- Receptors, Muscarinic
- Muscarinic Receptors
- Muscarinic Acetylcholine Receptors
- Acetylcholine Receptors, Muscarinic
- Receptors, Muscarinic Acetylcholine
- Muscarinic Acetylcholine Receptor
- Acetylcholine Receptor, Muscarinic
- Receptor, Muscarinic Acetylcholine
- Muscarinic Receptor
- Receptor, Muscarinic
|
Below are MeSH descriptors whose meaning is more general than "Receptors, Muscarinic".
Below are MeSH descriptors whose meaning is more specific than "Receptors, Muscarinic".
This graph shows the total number of publications written about "Receptors, Muscarinic" by people in this website by year, and whether "Receptors, Muscarinic" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 5 | 0 | 5 |
| 1996 | 2 | 1 | 3 |
| 1997 | 4 | 1 | 5 |
| 1998 | 3 | 0 | 3 |
| 1999 | 2 | 1 | 3 |
| 2000 | 1 | 1 | 2 |
| 2001 | 1 | 0 | 1 |
| 2002 | 1 | 1 | 2 |
| 2003 | 1 | 0 | 1 |
| 2010 | 0 | 1 | 1 |
| 2011 | 1 | 0 | 1 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Receptors, Muscarinic" by people in Profiles.
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Janeczko P, Norris MR, Bielory L. Assessment of receptor affinities of ophthalmic and systemic agents in dry eye disease. Curr Opin Allergy Clin Immunol. 2021 10 01; 21(5):480-485.
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Raufman JP, Cheng K, Saxena N, Chahdi A, Belo A, Khurana S, Xie G. Muscarinic receptor agonists stimulate matrix metalloproteinase 1-dependent invasion of human colon cancer cells. Biochem Biophys Res Commun. 2011 Nov 18; 415(2):319-24.
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Pavlakis PP, Alexopoulos H, Kosmidis ML, Stamboulis E, Routsias JG, Tzartos SJ, Tzioufas AG, Moutsopoulos HM, Dalakas MC. Peripheral neuropathies in Sjogren syndrome: a new reappraisal. J Neurol Neurosurg Psychiatry. 2011 Jul; 82(7):798-802.
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Murthy KS, Zhou H, Grider JR, Brautigan DL, Eto M, Makhlouf GM. Differential signalling by muscarinic receptors in smooth muscle: m2-mediated inactivation of myosin light chain kinase via Gi3, Cdc42/Rac1 and p21-activated kinase 1 pathway, and m3-mediated MLC20 (20 kDa regulatory light chain of myosin II) phosphorylation via Rho-associated kinase/myosin phosphatase targeting subunit 1 and protein kinase C/CPI-17 pathway. Biochem J. 2003 Aug 15; 374(Pt 1):145-55.
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Billington CK, Penn RB. m3 muscarinic acetylcholine receptor regulation in the airway. Am J Respir Cell Mol Biol. 2002 Mar; 26(3):269-72.
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Santini F, Gaidarov I, Keen JH. G protein-coupled receptor/arrestin3 modulation of the endocytic machinery. J Cell Biol. 2002 Feb 18; 156(4):665-76.
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Shui Z, Khan IA, Haga T, Benovic JL, Boyett MR. Control of the cardiac muscarinic K+ channel by beta-arrestin 2. J Biol Chem. 2001 Apr 13; 276(15):11691-7.
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Santini F, Penn RB, Gagnon AW, Benovic JL, Keen JH. Selective recruitment of arrestin-3 to clathrin coated pits upon stimulation of G protein-coupled receptors. J Cell Sci. 2000 Jul; 113 ( Pt 13):2463-70.
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Wu G, Bogatkevich GS, Mukhin YV, Benovic JL, Hildebrandt JD, Lanier SM. Identification of Gbetagamma binding sites in the third intracellular loop of the M(3)-muscarinic receptor and their role in receptor regulation. J Biol Chem. 2000 Mar 24; 275(12):9026-34.
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Mundell SJ, Loudon RP, Benovic JL. Characterization of G protein-coupled receptor regulation in antisense mRNA-expressing cells with reduced arrestin levels. Biochemistry. 1999 Jul 06; 38(27):8723-32.