Somatomedins

"Somatomedins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Insulin-like polypeptides made by the liver and some fibroblasts and released into the blood when stimulated by SOMATOTROPIN. They cause sulfate incorporation into collagen, RNA, and DNA synthesis, which are prerequisites to cell division and growth of the organism.

Descriptor ID	D013002
MeSH Number(s)	D12.644.276.937 D12.776.124.862 D12.776.467.937 D23.529.937
Concept/Terms	Somatomedins Somatomedins Sulfation Factor Factor, Sulfation Somatomedin Insulin Like Growth Factors Insulin-Like Growth Factors Factors, Insulin-Like Growth Growth Factors, Insulin-Like

Below are MeSH descriptors whose meaning is more general than "Somatomedins".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Intercellular Signaling Peptides and Proteins [D12.644.276]
Somatomedins [D12.644.276.937]
Proteins [D12.776]
Blood Proteins [D12.776.124]
Somatomedins [D12.776.124.862]
Intercellular Signaling Peptides and Proteins [D12.776.467]
Somatomedins [D12.776.467.937]
Biological Factors [D23]
Intercellular Signaling Peptides and Proteins [D23.529]
Somatomedins [D23.529.937]

Below are MeSH descriptors whose meaning is related to "Somatomedins".

Below are MeSH descriptors whose meaning is more specific than "Somatomedins".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Somatomedins" by people in this website by year, and whether "Somatomedins" was a major or minor topic of these publications.

Bar chart showing 13 publications over 10 distinct years, with a maximum of 3 publications in 2005

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2002	1	0	1
2005	2	1	3
2013	0	2	2
2014	0	1	1
2015	1	0	1
2017	0	1	1
2019	1	0	1
2021	1	0	1
2022	1	0	1
2024	0	1	1

Below are the most recent publications written about "Somatomedins" by people in Profiles.

Mancarella C, Morrione A, Scotlandi K. Extracellular Interactors of the IGF System: Impact on Cancer Hallmarks and Therapeutic Approaches. Int J Mol Sci. 2024 May 29; 25(11).

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Scalia P, Williams SJ, Fujita-Yamaguchi Y, Giordano A. Cell cycle control by the insulin-like growth factor signal: at the crossroad between cell growth and mitotic regulation. Cell Cycle. 2023 01; 22(1):1-37.

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Mancarella C, Morrione A, Scotlandi K. Novel Regulators of the IGF System in Cancer. Biomolecules. 2021 02 12; 11(2).

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Vella V, Malaguarnera R, Nicolosi ML, Morrione A, Belfiore A. Insulin/IGF signaling and discoidin domain receptors: An emerging functional connection. Biochim Biophys Acta Mol Cell Res. 2019 11; 1866(11):118522.

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Belfiore A, Malaguarnera R, Vella V, Lawrence MC, Sciacca L, Frasca F, Morrione A, Vigneri R. Insulin Receptor Isoforms in Physiology and Disease: An Updated View. Endocr Rev. 2017 10 01; 38(5):379-431.

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Tovar V, Cornella H, Moeini A, Vidal S, Hoshida Y, Sia D, Peix J, Cabellos L, Alsinet C, Torrecilla S, Martinez-Quetglas I, Lozano JJ, Desbois-Mouthon C, Sol? M, Domingo-Domenech J, Villanueva A, Llovet JM. Tumour initiating cells and IGF/FGF signalling contribute to sorafenib resistance in hepatocellular carcinoma. Gut. 2017 03; 66(3):530-540.

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Miettinen M, Lasota J. Succinate dehydrogenase deficient gastrointestinal stromal tumors (GISTs) - a review. Int J Biochem Cell Biol. 2014 Aug; 53:514-9.

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Eytan O, Morice-Picard F, Sarig O, Ezzedine K, Isakov O, Li Q, Ishida-Yamamoto A, Shomron N, Goldsmith T, Fuchs-Telem D, Adir N, Uitto J, Orlow SJ, Taieb A, Sprecher E. Cole Disease Results from Mutations in ENPP1. Am J Hum Genet. 2013 Oct 03; 93(4):752-7.

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Dean JP, Sprenger CC, Wan J, Haugk K, Ellis WJ, Lin DW, Corman JM, Dalkin BL, Mostaghel E, Nelson PS, Cohen P, Montgomery B, Plymate SR. Response of the insulin-like growth factor (IGF) system to IGF-IR inhibition and androgen deprivation in a neoadjuvant prostate cancer trial: effects of obesity and androgen deprivation. J Clin Endocrinol Metab. 2013 May; 98(5):E820-8.

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Meyerhardt JA, Sloan JA, Sargent DJ, Goldberg RM, Pollak M, Morton RF, Ramanathan RK, Williamson SK, Findlay BP, Fuchs CS. Associations between plasma insulin-like growth factor proteins and C-peptide and quality of life in patients with metastatic colorectal cancer. Cancer Epidemiol Biomarkers Prev. 2005 Jun; 14(6):1402-10.

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