Receptors, Calcitonin Gene-Related Peptide
"Receptors, Calcitonin Gene-Related Peptide" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cell surface proteins that bind CALCITONIN GENE-RELATED PEPTIDE with high affinity and trigger intracellular changes which influence the behavior of cells. CGRP receptors are present in both the CENTRAL NERVOUS SYSTEM and the periphery. They are formed via the heterodimerization of the CALCITONIN RECEPTOR-LIKE PROTEIN and RECEPTOR ACTIVITY-MODIFYING PROTEIN 1.
| Descriptor ID |
D018015
|
| MeSH Number(s) |
D12.776.543.750.695.105 D12.776.543.750.720.600.260 D12.776.543.750.750.555.260
|
| Concept/Terms |
Receptors, Calcitonin Gene-Related Peptide- Receptors, Calcitonin Gene-Related Peptide
- Receptors, Calcitonin Gene Related Peptide
- Calcitonin Gene-Related Peptide Receptors
- Calcitonin Gene Related Peptide Receptors
- Receptors, CGRP
- CGRP Receptor
- CGRP Receptors
- Calcitonin-Gene Related Peptide Receptor
- Calcitonin Gene Related Peptide Receptor
|
Below are MeSH descriptors whose meaning is more general than "Receptors, Calcitonin Gene-Related Peptide".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, G-Protein-Coupled [D12.776.543.750.695]
- Receptors, Calcitonin Gene-Related Peptide [D12.776.543.750.695.105]
- Receptors, Neurotransmitter [D12.776.543.750.720]
- Receptors, Neuropeptide [D12.776.543.750.720.600]
- Receptors, Calcitonin Gene-Related Peptide [D12.776.543.750.720.600.260]
- Receptors, Peptide [D12.776.543.750.750]
- Receptors, Neuropeptide [D12.776.543.750.750.555]
- Receptors, Calcitonin Gene-Related Peptide [D12.776.543.750.750.555.260]
Below are MeSH descriptors whose meaning is more specific than "Receptors, Calcitonin Gene-Related Peptide".
This graph shows the total number of publications written about "Receptors, Calcitonin Gene-Related Peptide" by people in this website by year, and whether "Receptors, Calcitonin Gene-Related Peptide" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2011 | 0 | 1 | 1 |
| 2016 | 0 | 1 | 1 |
| 2017 | 3 | 0 | 3 |
| 2018 | 0 | 2 | 2 |
| 2019 | 1 | 0 | 1 |
| 2022 | 0 | 1 | 1 |
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click here.
Below are the most recent publications written about "Receptors, Calcitonin Gene-Related Peptide" by people in Profiles.
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Cohen F, Yuan H, Silberstein SD. Calcitonin Gene-Related Peptide (CGRP)-Targeted Monoclonal Antibodies and Antagonists in Migraine: Current Evidence and Rationale. BioDrugs. 2022 May; 36(3):341-358.
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Dodick DW. CGRP ligand and receptor monoclonal antibodies for migraine prevention: Evidence review and clinical implications. Cephalalgia. 2019 03; 39(3):445-458.
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Tepper SJ. Anti-Calcitonin Gene-Related Peptide (CGRP) Therapies: Update on a Previous Review After the American Headache Society 60th Scientific Meeting, San Francisco, June 2018. Headache. 2018 11; 58 Suppl 3:276-290.
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Tepper SJ. History and Review of anti-Calcitonin Gene-Related Peptide (CGRP) Therapies: From Translational Research to Treatment. Headache. 2018 11; 58 Suppl 3:238-275.
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Silberstein SD, Dodick DW, Bigal ME, Yeung PP, Goadsby PJ, Blankenbiller T, Grozinski-Wolff M, Yang R, Ma Y, Aycardi E. Fremanezumab for the Preventive Treatment of Chronic Migraine. N Engl J Med. 2017 11 30; 377(22):2113-2122.
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Ashina M, Dodick D, Goadsby PJ, Reuter U, Silberstein S, Zhang F, Gage JR, Cheng S, Mikol DD, Lenz RA. Erenumab (AMG 334) in episodic migraine: Interim analysis of an ongoing open-label study. Neurology. 2017 Sep 19; 89(12):1237-1243.
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Tepper S, Ashina M, Reuter U, Brandes JL, Doležil D, Silberstein S, Winner P, Leonardi D, Mikol D, Lenz R. Safety and efficacy of erenumab for preventive treatment of chronic migraine: a randomised, double-blind, placebo-controlled phase 2 trial. Lancet Neurol. 2017 Jun; 16(6):425-434.
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Rice FL, Xie JY, Albrecht PJ, Acker E, Bourgeois J, Navratilova E, Dodick DW, Porreca F. Anatomy and immunochemical characterization of the non-arterial peptidergic diffuse dural innervation of the rat and Rhesus monkey: Implications for functional regulation and treatment in migraine. Cephalalgia. 2017 Dec; 37(14):1350-1372.
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Marmura MJ, Silberstein SD. Current understanding and treatment of headache disorders: five new things. Neurology. 2011 Feb 15; 76(7 Suppl 2):S31-6.