Receptors, Corticotropin-Releasing Hormone
"Receptors, Corticotropin-Releasing Hormone" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cell surface proteins that bind corticotropin-releasing hormone with high affinity and trigger intracellular changes which influence the behavior of cells. The corticotropin releasing-hormone receptors on anterior pituitary cells mediate the stimulation of corticotropin release by hypothalamic corticotropin releasing factor. The physiological consequence of activating corticotropin-releasing hormone receptors on central neurons is not well understood.
| Descriptor ID |
D018019
|
| MeSH Number(s) |
D12.776.543.750.695.180 D12.776.543.750.720.600.290 D12.776.543.750.750.555.290 D12.776.543.750.750.700.150
|
| Concept/Terms |
Receptors, Corticotropin-Releasing Hormone- Receptors, Corticotropin-Releasing Hormone
- Corticotropin-Releasing Hormone Receptors
- Hormone Receptors, Corticotropin-Releasing
- Receptors, Corticotropin Releasing Hormone
- Corticotropin Releasing-Hormone Receptors
- Corticotropin Releasing Hormone Receptors
- Receptors, Corticotropin Releasing-Hormone
- Releasing-Hormone Receptors, Corticotropin
- CRF Receptors
- Corticotropin Releasing-Factor Receptors
- Corticotropin Releasing Factor Receptors
- Receptors, Corticotropin Releasing-Factor
- Releasing-Factor Receptors, Corticotropin
- Receptors, CRF
- CRH Receptor
- Receptor, CRH
- CRH Receptors
- Receptors, CRH
- Corticotropin Releasing-Hormone Receptor
- Corticotropin Releasing Hormone Receptor
- Receptor, Corticotropin Releasing-Hormone
- Releasing-Hormone Receptor, Corticotropin
- CRF Receptor
- Receptor, CRF
|
Below are MeSH descriptors whose meaning is more general than "Receptors, Corticotropin-Releasing Hormone".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, G-Protein-Coupled [D12.776.543.750.695]
- Receptors, Corticotropin-Releasing Hormone [D12.776.543.750.695.180]
- Receptors, Neurotransmitter [D12.776.543.750.720]
- Receptors, Neuropeptide [D12.776.543.750.720.600]
- Receptors, Corticotropin-Releasing Hormone [D12.776.543.750.720.600.290]
- Receptors, Peptide [D12.776.543.750.750]
- Receptors, Neuropeptide [D12.776.543.750.750.555]
- Receptors, Corticotropin-Releasing Hormone [D12.776.543.750.750.555.290]
- Receptors, Pituitary Hormone-Regulating Hormone [D12.776.543.750.750.700]
- Receptors, Corticotropin-Releasing Hormone [D12.776.543.750.750.700.150]
Below are MeSH descriptors whose meaning is more specific than "Receptors, Corticotropin-Releasing Hormone".
This graph shows the total number of publications written about "Receptors, Corticotropin-Releasing Hormone" by people in this website by year, and whether "Receptors, Corticotropin-Releasing Hormone" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 1 | 0 | 1 |
| 2006 | 2 | 0 | 2 |
| 2007 | 1 | 0 | 1 |
| 2009 | 1 | 0 | 1 |
| 2011 | 0 | 1 | 1 |
| 2012 | 0 | 2 | 2 |
| 2015 | 0 | 1 | 1 |
| 2016 | 1 | 0 | 1 |
| 2022 | 1 | 0 | 1 |
| 2023 | 0 | 1 | 1 |
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click here.
Below are the most recent publications written about "Receptors, Corticotropin-Releasing Hormone" by people in Profiles.
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Amin M, Horst N, Wu R, Gragnoli C. Novel corticotropin-releasing hormone receptor genes (CRHR1 and CRHR2) linkage to and association with polycystic ovary syndrome. J Ovarian Res. 2023 Aug 05; 16(1):155.
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Amin M, Ott J, Gordon D, Wu R, Postolache TT, Vergare M, Gragnoli C. Comorbidity of Novel CRHR2 Gene Variants in Type 2 Diabetes and Depression. Int J Mol Sci. 2022 Aug 29; 23(17).
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Shenoda BB, Alexander GM, Ajit SK. Hsa-miR-34a mediated repression of corticotrophin releasing hormone receptor 1 regulates pro-opiomelanocortin expression in patients with complex regional pain syndrome. J Transl Med. 2016 Mar 03; 14:64.
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Kwako LE, Spagnolo PA, Schwandt ML, Thorsell A, George DT, Momenan R, Rio DE, Huestis M, Anizan S, Concheiro M, Sinha R, Heilig M. The corticotropin releasing hormone-1 (CRH1) receptor antagonist pexacerfont in alcohol dependence: a randomized controlled experimental medicine study. Neuropsychopharmacology. 2015 Mar 13; 40(5):1053-63.
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Lemos JC, Wanat MJ, Smith JS, Reyes BA, Hollon NG, Van Bockstaele EJ, Chavkin C, Phillips PE. Severe stress switches CRF action in the nucleus accumbens from appetitive to aversive. Nature. 2012 Oct 18; 490(7420):402-6.
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Gragnoli C. Depression and type 2 diabetes: cortisol pathway implication and investigational needs. J Cell Physiol. 2012 Jun; 227(6):2318-22.
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Waselus M, Valentino RJ, Van Bockstaele EJ. Collateralized dorsal raphe nucleus projections: a mechanism for the integration of diverse functions during stress. J Chem Neuroanat. 2011 Jul; 41(4):266-80.
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Waselus M, Nazzaro C, Valentino RJ, Van Bockstaele EJ. Stress-induced redistribution of corticotropin-releasing factor receptor subtypes in the dorsal raphe nucleus. Biol Psychiatry. 2009 Jul 1; 66(1):76-83.
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Reyes BA, Valentino RJ, Van Bockstaele EJ. Stress-induced intracellular trafficking of corticotropin-releasing factor receptors in rat locus coeruleus neurons. Endocrinology. 2008 Jan; 149(1):122-30.
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Reyes BA, Glaser JD, Van Bockstaele EJ. Ultrastructural evidence for co-localization of corticotropin-releasing factor receptor and mu-opioid receptor in the rat nucleus locus coeruleus. Neurosci Lett. 2007 Feb 21; 413(3):216-21.