Monomeric GTP-Binding Proteins

"Monomeric GTP-Binding Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A class of monomeric, low molecular weight (20-25 kDa) GTP-binding proteins that regulate a variety of intracellular processes. The GTP bound form of the protein is active and limited by its inherent GTPase activity, which is controlled by an array of GTPase activators, GDP dissociation inhibitors, and guanine nucleotide exchange factors. This enzyme was formerly listed as EC 3.6.1.47

Descriptor ID	D020559
MeSH Number(s)	D08.811.277.040.330.300.400 D12.644.360.525 D12.776.157.325.515 D12.776.476.525
Concept/Terms	Monomeric GTP-Binding Proteins Monomeric GTP-Binding Proteins Monomeric GTP Binding Proteins Small GTPases GTPases, Small Monomeric G-Proteins Monomeric G Proteins Small G-Proteins G-Proteins, Small Small G Proteins G-Proteins, Monomeric G Proteins, Monomeric GTP-Binding Proteins, Monomeric GTP Binding Proteins, Monomeric ras-Related GTPases ras-Related GTPases GTPases, ras-Related ras Related GTPases ras-Related GTP-Binding Proteins GTP-Binding Proteins, ras-Related Proteins, ras-Related GTP-Binding ras Related GTP Binding Proteins ras-Related G-Proteins G-Proteins, ras-Related ras Related G Proteins

Below are MeSH descriptors whose meaning is more general than "Monomeric GTP-Binding Proteins".

Chemicals and Drugs [D]
Enzymes and Coenzymes [D08]
Enzymes [D08.811]
Hydrolases [D08.811.277]
Acid Anhydride Hydrolases [D08.811.277.040]
GTP Phosphohydrolases [D08.811.277.040.330]
GTP-Binding Proteins [D08.811.277.040.330.300]
Monomeric GTP-Binding Proteins [D08.811.277.040.330.300.400]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Intracellular Signaling Peptides and Proteins [D12.644.360]
Monomeric GTP-Binding Proteins [D12.644.360.525]
Proteins [D12.776]
Carrier Proteins [D12.776.157]
GTP-Binding Proteins [D12.776.157.325]
Monomeric GTP-Binding Proteins [D12.776.157.325.515]
Intracellular Signaling Peptides and Proteins [D12.776.476]
Monomeric GTP-Binding Proteins [D12.776.476.525]

Below are MeSH descriptors whose meaning is related to "Monomeric GTP-Binding Proteins".

Below are MeSH descriptors whose meaning is more specific than "Monomeric GTP-Binding Proteins".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Monomeric GTP-Binding Proteins" by people in this website by year, and whether "Monomeric GTP-Binding Proteins" was a major or minor topic of these publications.

Bar chart showing 17 publications over 13 distinct years, with a maximum of 2 publications in 1997 and 2000 and 2008 and 2013

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	1	0	1
1997	2	0	2
2000	1	1	2
2001	1	0	1
2003	1	0	1
2005	0	1	1
2008	1	1	2
2010	1	0	1
2011	0	1	1
2013	1	1	2
2014	0	1	1
2016	1	0	1
2019	1	0	1

Below are the most recent publications written about "Monomeric GTP-Binding Proteins" by people in Profiles.

Petit V, Raymond J, Alberti C, Pouteaux M, Gallagher SJ, Nguyen MQ, Aplin AE, Delmas V, Larue L. C57BL/6 congenic mouse NRASQ61K melanoma cell lines are highly sensitive to the combination of Mek and Akt inhibitors in vitro and in vivo. Pigment Cell Melanoma Res. 2019 11; 32(6):829-841.

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Kohnken R, Kodigepalli KM, Mishra A, Porcu P, Wu L. MicroRNA-181 contributes to downregulation of SAMHD1 expression in CD4+ T-cells derived from S?zary syndrome patients. Leuk Res. 2017 Jan; 52:58-66.

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Mack SG, Cook DJ, Dhurjati P, Butchbach ME. Systems biology investigation of cAMP modulation to increase SMN levels for the treatment of spinal muscular atrophy. PLoS One. 2014; 9(12):e115473.

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de Silva S, Wang F, Hake TS, Porcu P, Wong HK, Wu L. Downregulation of SAMHD1 expression correlates with promoter DNA methylation in S?zary syndrome patients. J Invest Dermatol. 2014 Feb; 134(2):562-565.

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Chen Y, Khan RS, Cwanger A, Song Y, Steenstra C, Bang S, Cheah JH, Dunaief J, Shindler KS, Snyder SH, Kim SF. Dexras1, a small GTPase, is required for glutamate-NMDA neurotoxicity. J Neurosci. 2013 Feb 20; 33(8):3582-7.

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Jhun BS, O-Uchi J, Wang W, Ha CH, Zhao J, Kim JY, Wong C, Dirksen RT, Lopes CMB, Jin ZG. Adrenergic signaling controls RGK-dependent trafficking of cardiac voltage-gated L-type Ca2+ channels through PKD1. Circ Res. 2012 Jan 06; 110(1):59-70.

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Quintero CA, Giraudo CG, Villarreal M, Montich G, Maccioni HJ. Identification of a site in Sar1 involved in the interaction with the cytoplasmic tail of glycolipid glycosyltransferases. J Biol Chem. 2010 Sep 24; 285(39):30340-6.

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Barthold JS, McCahan SM, Singh AV, Knudsen TB, Si X, Campion L, Akins RE. Altered expression of muscle- and cytoskeleton-related genes in a rat strain with inherited cryptorchidism. J Androl. 2008 May-Jun; 29(3):352-66.

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Kerr BA, Otani T, Koyama E, Freeman TA, Enomoto-Iwamoto M. Small GTPase protein Rac-1 is activated with maturation and regulates cell morphology and function in chondrocytes. Exp Cell Res. 2008 Apr 01; 314(6):1301-12.

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Brando C, Mukhopadhyay S, Kovacs E, Medina R, Patel P, Catina TL, Campbell KS, Santoli D. Receptors and lytic mediators regulating anti-tumor activity by the leukemic killer T cell line TALL-104. J Leukoc Biol. 2005 Aug; 78(2):359-71.

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