ran GTP-Binding Protein

"ran GTP-Binding Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A monomeric GTP-binding protein involved in nucleocytoplasmic transport of proteins into the nucleus and RNA into the cytoplasm. This enzyme was formerly listed as EC 3.6.1.47.

Descriptor ID	D020931
MeSH Number(s)	D08.811.277.040.330.300.400.462 D12.644.360.525.462 D12.776.157.325.515.462 D12.776.157.530.750.750 D12.776.476.525.462 D12.776.543.585.750.750 D12.776.660.768
Concept/Terms	ran GTP-Binding Protein ran GTP-Binding Protein GTP-Binding Protein, ran ran GTP Binding Protein ras-Related Nuclear Protein Nuclear Protein, ras-Related ras Related Nuclear Protein ran Proteins TC4 Protein ran Protein

Below are MeSH descriptors whose meaning is more general than "ran GTP-Binding Protein".

Chemicals and Drugs [D]
Enzymes and Coenzymes [D08]
Enzymes [D08.811]
Hydrolases [D08.811.277]
Acid Anhydride Hydrolases [D08.811.277.040]
GTP Phosphohydrolases [D08.811.277.040.330]
GTP-Binding Proteins [D08.811.277.040.330.300]
Monomeric GTP-Binding Proteins [D08.811.277.040.330.300.400]
ran GTP-Binding Protein [D08.811.277.040.330.300.400.462]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Intracellular Signaling Peptides and Proteins [D12.644.360]
Monomeric GTP-Binding Proteins [D12.644.360.525]
ran GTP-Binding Protein [D12.644.360.525.462]
Proteins [D12.776]
Carrier Proteins [D12.776.157]
GTP-Binding Proteins [D12.776.157.325]
Monomeric GTP-Binding Proteins [D12.776.157.325.515]
ran GTP-Binding Protein [D12.776.157.325.515.462]
Membrane Transport Proteins [D12.776.157.530]
Nucleocytoplasmic Transport Proteins [D12.776.157.530.750]
ran GTP-Binding Protein [D12.776.157.530.750.750]
Intracellular Signaling Peptides and Proteins [D12.776.476]
Monomeric GTP-Binding Proteins [D12.776.476.525]
ran GTP-Binding Protein [D12.776.476.525.462]
Membrane Proteins [D12.776.543]
Membrane Transport Proteins [D12.776.543.585]
Nucleocytoplasmic Transport Proteins [D12.776.543.585.750]
ran GTP-Binding Protein [D12.776.543.585.750.750]
Nuclear Proteins [D12.776.660]
ran GTP-Binding Protein [D12.776.660.768]

Below are MeSH descriptors whose meaning is related to "ran GTP-Binding Protein".

Below are MeSH descriptors whose meaning is more specific than "ran GTP-Binding Protein".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "ran GTP-Binding Protein" by people in this website by year, and whether "ran GTP-Binding Protein" was a major or minor topic of these publications.

Bar chart showing 9 publications over 8 distinct years, with a maximum of 2 publications in 2010

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1998	0	1	1
2003	0	1	1
2008	1	0	1
2009	0	1	1
2010	0	2	2
2014	0	1	1
2017	0	1	1
2024	1	0	1

Below are the most recent publications written about "ran GTP-Binding Protein" by people in Profiles.

Nelson AT, Cicardi ME, Markandaiah SS, Han JY, Philp NJ, Welebob E, Haeusler AR, Pasinelli P, Manfredi G, Kawamata H, Trotti D. Glucose hypometabolism prompts RAN translation and exacerbates C9orf72-related ALS/FTD phenotypes. EMBO Rep. 2024 05; 25(5):2479-2510.

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Connell M, Chen H, Jiang J, Kuan CW, Fotovati A, Chu TL, He Z, Lengyell TC, Li H, Kroll T, Li AM, Goldowitz D, Frappart L, Ploubidou A, Patel MS, Pilarski LM, Simpson EM, Lange PF, Allan DW, Maxwell CA. HMMR acts in the PLK1-dependent spindle positioning pathway and supports neural development. Elife. 2017 10 10; 6.

View in: PubMed
Lieu KG, Shim EH, Wang J, Lokareddy RK, Tao T, Cingolani G, Zambetti GP, Jans DA. The p53-induced factor Ei24 inhibits nuclear import through an importin ?-binding-like domain. J Cell Biol. 2014 May 12; 205(3):301-12.

View in: PubMed
Melo SA, Moutinho C, Ropero S, Calin GA, Rossi S, Spizzo R, Fernandez AF, Davalos V, Villanueva A, Montoya G, Yamamoto H, Schwartz S, Esteller M. A genetic defect in exportin-5 traps precursor microRNAs in the nucleus of cancer cells. Cancer Cell. 2010 Oct 19; 18(4):303-15.

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Lott K, Bhardwaj A, Mitrousis G, Pante N, Cingolani G. The importin beta binding domain modulates the avidity of importin beta for the nuclear pore complex. J Biol Chem. 2010 Apr 30; 285(18):13769-80.

View in: PubMed
Debler EW, Blobel G, Hoelz A. Nuclear transport comes full circle. Nat Struct Mol Biol. 2009 May; 16(5):457-9.

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Yudin D, Hanz S, Yoo S, Iavnilovitch E, Willis D, Gradus T, Vuppalanchi D, Segal-Ruder Y, Ben-Yaakov K, Hieda M, Yoneda Y, Twiss JL, Fainzilber M. Localized regulation of axonal RanGTPase controls retrograde injury signaling in peripheral nerve. Neuron. 2008 Jul 31; 59(2):241-52.

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Lavia P, Mileo AM, Giordano A, Paggi MG. Emerging roles of DNA tumor viruses in cell proliferation: new insights into genomic instability. Oncogene. 2003 Sep 29; 22(42):6508-16.

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Milano J, Strayer DS. Effects of overexpression of Ran/TC4 mammalian cells in vitro. Exp Cell Res. 1998 Feb 25; 239(1):31-9.

View in: PubMed

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