Autophagy-Related Protein-1 Homolog
"Autophagy-Related Protein-1 Homolog" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A serine/threonine-protein kinase that functions in AUTOPHAGY in response to starvation. It acts on the PHOSPHATIDYLINOSITOL 3-KINASE complex PIK3C3 to regulate AUTOPHAGOSOME formation. It also functions as both a downstream effector and negative regulator of mammalian target of rapamycin complex 1 (mTORC1) and is activated by AMPK, which it also negatively regulates.
| Descriptor ID |
D000071189
|
| MeSH Number(s) |
D08.811.913.696.620.682.700.108 D12.644.360.081 D12.776.094.438 D12.776.476.078
|
| Concept/Terms |
Autophagy-Related Protein-1 Homolog- Autophagy-Related Protein-1 Homolog
- Autophagy Related Protein 1 Homolog
- Serine-Threonine Protein Kinase ULK1
- Serine Threonine Protein Kinase ULK1
- Unc-51 Like Autophagy Activating Kinase 1
- Unc 51 Like Autophagy Activating Kinase 1
- ULK1 Protein
- Unc-51-Like Kinase 1
- Unc 51 Like Kinase 1
|
Below are MeSH descriptors whose meaning is more general than "Autophagy-Related Protein-1 Homolog".
Below are MeSH descriptors whose meaning is more specific than "Autophagy-Related Protein-1 Homolog".
This graph shows the total number of publications written about "Autophagy-Related Protein-1 Homolog" by people in this website by year, and whether "Autophagy-Related Protein-1 Homolog" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2013 | 0 | 1 | 1 |
| 2017 | 0 | 1 | 1 |
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Below are the most recent publications written about "Autophagy-Related Protein-1 Homolog" by people in Profiles.
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Liu C, Choi H, Johnson ZI, Tian J, Shapiro IM, Risbud MV. Lack of evidence for involvement of TonEBP and hyperosmotic stimulus in induction of autophagy in the nucleus pulposus. Sci Rep. 2017 07 03; 7(1):4543.
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Caino MC, Chae YC, Vaira V, Ferrero S, Nosotti M, Martin NM, Weeraratna A, O'Connell M, Jernigan D, Fatatis A, Languino LR, Bosari S, Altieri DC. Metabolic stress regulates cytoskeletal dynamics and metastasis of cancer cells. J Clin Invest. 2013 Jul; 123(7):2907-20.