Peroxisome Proliferator-Activated Receptors

"Peroxisome Proliferator-Activated Receptors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

TRANSCRIPTION FACTORS that are activated by ligands and heterodimerize with RETINOID X RECEPTORS and bind to peroxisome proliferator response elements in the promoter regions of target genes.

Descriptor ID	D047492
MeSH Number(s)	D12.776.826.239 D12.776.930.705
Concept/Terms	Peroxisome Proliferator-Activated Receptors Peroxisome Proliferator-Activated Receptors Peroxisome Proliferator Activated Receptors Proliferator-Activated Receptors, Peroxisome Receptors, Peroxisome Proliferator-Activated PPAR NUC1 PPAR NUC1 PPAR PPAR, NUC1

Below are MeSH descriptors whose meaning is more general than "Peroxisome Proliferator-Activated Receptors".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Receptors, Cytoplasmic and Nuclear [D12.776.826]
Peroxisome Proliferator-Activated Receptors [D12.776.826.239]
Transcription Factors [D12.776.930]
Peroxisome Proliferator-Activated Receptors [D12.776.930.705]

Below are MeSH descriptors whose meaning is related to "Peroxisome Proliferator-Activated Receptors".

Below are MeSH descriptors whose meaning is more specific than "Peroxisome Proliferator-Activated Receptors".

Peroxisome Proliferator-Activated Receptors
PPAR alpha
PPAR delta
PPAR gamma
PPAR-beta

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Peroxisome Proliferator-Activated Receptors" by people in this website by year, and whether "Peroxisome Proliferator-Activated Receptors" was a major or minor topic of these publications.

Bar chart showing 9 publications over 8 distinct years, with a maximum of 2 publications in 2009

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2004	1	0	1
2005	1	0	1
2008	0	1	1
2009	2	0	2
2010	1	0	1
2011	0	1	1
2012	1	0	1
2017	1	0	1

Below are the most recent publications written about "Peroxisome Proliferator-Activated Receptors" by people in Profiles.

Borland MG, Yao PL, Kehres EM, Lee C, Pritzlaff AM, Ola E, Wagner AL, Shannon BE, Albrecht PP, Zhu B, Kang BH, Robertson GP, Gonzalez FJ, Peters JM. Editor's Highlight: PPAR?/d and PPAR? Inhibit Melanoma Tumorigenicity by Modulating Inflammation and Apoptosis. Toxicol Sci. 2017 10 01; 159(2):436-448.

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Peters JM, Shah YM, Gonzalez FJ. The role of peroxisome proliferator-activated receptors in carcinogenesis and chemoprevention. Nat Rev Cancer. 2012 Feb 09; 12(3):181-95.

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Peters JM, Gonzalez FJ. Why toxic equivalency factors are not suitable for perfluoroalkyl chemicals. Chem Res Toxicol. 2011 Oct 17; 24(10):1601-9.

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Palkar PS, Borland MG, Naruhn S, Ferry CH, Lee C, Sk UH, Sharma AK, Amin S, Murray IA, Anderson CR, Perdew GH, Gonzalez FJ, M?ller R, Peters JM. Cellular and pharmacological selectivity of the peroxisome proliferator-activated receptor-beta/delta antagonist GSK3787. Mol Pharmacol. 2010 Sep; 78(3):419-30.

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Biscetti F, Straface G, Pitocco D, Zaccardi F, Ghirlanda G, Flex A. Peroxisome proliferator-activated receptors and angiogenesis. Nutr Metab Cardiovasc Dis. 2009 Dec; 19(11):751-9.

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Roman J. Moving away from PPARs - EGFR signaling and the anti-cancer effects of thiazolinedinediones. Cell Res. 2009 Jun; 19(6):669-71.

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Gopinathan L, Hannon DB, Peters JM, Vanden Heuvel JP. Regulation of peroxisome proliferator-activated receptor-alpha by MDM2. Toxicol Sci. 2009 Mar; 108(1):48-58.

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Peraza MA, Burdick AD, Marin HE, Gonzalez FJ, Peters JM. The toxicology of ligands for peroxisome proliferator-activated receptors (PPAR). Toxicol Sci. 2006 Apr; 90(2):269-95.

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Bility MT, Thompson JT, McKee RH, David RM, Butala JH, Vanden Heuvel JP, Peters JM. Activation of mouse and human peroxisome proliferator-activated receptors (PPARs) by phthalate monoesters. Toxicol Sci. 2004 Nov; 82(1):170-82.

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