"Mucin-4" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A transmembrane mucin that is found in a broad variety of epithelial tissue. Mucin-4 may play a role in regulating cellular adhesion and in cell surface signaling from the ERBB-2 RECEPTOR PROTEIN-TYROSINE KINASE. Mucin-4 is a heterodimer of alpha and beta chains. The alpha and beta chains result from the proteolytic cleavage of a precursor protein.
Descriptor ID |
D055264
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MeSH Number(s) |
D12.644.360.534 D12.776.395.560.631.195 D12.776.476.534
|
Concept/Terms |
Mucin-4 alpha chain- Mucin-4 alpha chain
- Mucin 4 alpha chain
- Ascites Sialoglycoprotein 1
- Sialoglycoprotein 1, Ascites
- ASGP-1
|
Below are MeSH descriptors whose meaning is more general than "Mucin-4".
Below are MeSH descriptors whose meaning is more specific than "Mucin-4".
This graph shows the total number of publications written about "Mucin-4" by people in this website by year, and whether "Mucin-4" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2002 | 0 | 1 | 1 |
2006 | 0 | 1 | 1 |
2010 | 1 | 0 | 1 |
2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Mucin-4" by people in Profiles.
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Righi A, Pacheco M, Pipola V, Gambarotti M, Benini S, Sbaraglia M, Frisoni T, Boriani S, Dei Tos AP, Gasbarrini A. Primary sclerosing epithelioid fibrosarcoma of the spine: a single-institution experience. Histopathology. 2021 Jun; 78(7):976-986.
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Torres MP, Ponnusamy MP, Chakraborty S, Smith LM, Das S, Arafat HA, Batra SK. Effects of thymoquinone in the expression of mucin 4 in pancreatic cancer cells: implications for the development of novel cancer therapies. Mol Cancer Ther. 2010 May; 9(5):1419-31.
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Moehle C, Ackermann N, Langmann T, Aslanidis C, Kel A, Kel-Margoulis O, Schmitz-Madry A, Zahn A, Stremmel W, Schmitz G. Aberrant intestinal expression and allelic variants of mucin genes associated with inflammatory bowel disease. J Mol Med (Berl). 2006 Dec; 84(12):1055-66.
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Swartz MJ, Batra SK, Varshney GC, Hollingsworth MA, Yeo CJ, Cameron JL, Wilentz RE, Hruban RH, Argani P. MUC4 expression increases progressively in pancreatic intraepithelial neoplasia. Am J Clin Pathol. 2002 May; 117(5):791-6.