Below are the most recent publications written about "DNA-Directed DNA Polymerase" by people in Profiles.
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Ito F, Li Z, Minakhin L, Chandramouly G, Tyagi M, Betsch R, Krais JJ, Taberi B, Vekariya U, Calbert M, Skorski T, Johnson N, Chen XS, Pomerantz RT. Structural basis for a Pol? helicase small-molecule inhibitor revealed by cryo-EM. Nat Commun. 2024 Aug 14; 15(1):7003.
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Vekariya U, Minakhin L, Chandramouly G, Tyagi M, Kent T, Sullivan-Reed K, Atkins J, Ralph D, Nieborowska-Skorska M, Kukuyan AM, Tang HY, Pomerantz RT, Skorski T. PARG is essential for Pol?-mediated DNA end-joining by removing repressive poly-ADP-ribose marks. Nat Commun. 2024 Jul 11; 15(1):5822.
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Fried W, Tyagi M, Minakhin L, Chandramouly G, Tredinnick T, Ramanjulu M, Auerbacher W, Calbert M, Rusanov T, Hoang T, Borisonnik N, Betsch R, Krais JJ, Wang Y, Vekariya UM, Gordon J, Morton G, Kent T, Skorski T, Johnson N, Childers W, Chen XS, Pomerantz RT. Discovery of a small-molecule inhibitor that traps Pol? on DNA and synergizes with PARP inhibitors. Nat Commun. 2024 Apr 05; 15(1):2862.
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Buchel G, Nayak AR, Herbine K, Sarfallah A, Sokolova VO, Zamudio-Ochoa A, Temiakov D. Structural basis for DNA proofreading. Nat Commun. 2023 Dec 27; 14(1):8501.
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Vandenberg BN, Laughery MF, Cordero C, Plummer D, Mitchell D, Kreyenhagen J, Albaqshi F, Brown AJ, Mieczkowski PA, Wyrick JJ, Roberts SA. Contributions of replicative and translesion DNA polymerases to mutagenic bypass of canonical and atypical UV photoproducts. Nat Commun. 2023 05 04; 14(1):2576.
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Black SJ, Ozdemir AY, Kashkina E, Kent T, Rusanov T, Ristic D, Shin Y, Suma A, Hoang T, Chandramouly G, Siddique LA, Borisonnik N, Sullivan-Reed K, Mallon JS, Skorski T, Carnevale V, Murakami KS, Wyman C, Pomerantz RT. Molecular basis of microhomology-mediated end-joining by purified full-length Pol?. Nat Commun. 2019 09 27; 10(1):4423.
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Thomas C, Rusanov T, Hoang T, Augustin T, Kent T, Gaspar I, Pomerantz RT. One-step enzymatic modification of RNA 3' termini using polymerase ?. Nucleic Acids Res. 2019 04 23; 47(7):3272-3283.
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Ozdemir AY, Rusanov T, Kent T, Siddique LA, Pomerantz RT. Polymerase ?-helicase efficiently unwinds DNA and RNA-DNA hybrids. J Biol Chem. 2018 04 06; 293(14):5259-5269.
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Mateos-Gomez PA, Kent T, Deng SK, McDevitt S, Kashkina E, Hoang TM, Pomerantz RT, Sfeir A. The helicase domain of Pol? counteracts RPA to promote alt-NHEJ. Nat Struct Mol Biol. 2017 Dec; 24(12):1116-1123.
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Fong K, Bailey CV, Tuttle P, Cunningham B, McGrath JA, Cho RJ. Questioning the Clinical Utility of Exome Sequencing in Developing Countries. Pediatr Dermatol. 2017 Jan; 34(1):e32-e34.