"Fibrinogen" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Plasma glycoprotein clotted by thrombin, composed of a dimer of three non-identical pairs of polypeptide chains (alpha, beta, gamma) held together by disulfide bonds. Fibrinogen clotting is a sol-gel change involving complex molecular arrangements: whereas fibrinogen is cleaved by thrombin to form polypeptides A and B, the proteolytic action of other enzymes yields different fibrinogen degradation products.
| Descriptor ID |
D005340
|
| MeSH Number(s) |
D12.776.124.050.250 D12.776.124.125.500 D12.776.811.300 D23.119.490
|
| Concept/Terms |
Fibrinogen- Fibrinogen
- Blood Coagulation Factor I
- Coagulation Factor I
- Factor I, Coagulation
- Factor I
|
Below are MeSH descriptors whose meaning is more general than "Fibrinogen".
Below are MeSH descriptors whose meaning is more specific than "Fibrinogen".
This graph shows the total number of publications written about "Fibrinogen" by people in this website by year, and whether "Fibrinogen" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 3 | 1 | 4 |
| 1996 | 2 | 1 | 3 |
| 1997 | 1 | 0 | 1 |
| 1998 | 1 | 2 | 3 |
| 2000 | 1 | 3 | 4 |
| 2002 | 0 | 4 | 4 |
| 2003 | 3 | 3 | 6 |
| 2004 | 1 | 2 | 3 |
| 2005 | 2 | 2 | 4 |
| 2006 | 1 | 1 | 2 |
| 2007 | 0 | 2 | 2 |
| 2008 | 1 | 2 | 3 |
| 2009 | 1 | 2 | 3 |
| 2010 | 2 | 1 | 3 |
| 2011 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
| 2018 | 0 | 2 | 2 |
| 2019 | 0 | 2 | 2 |
| 2020 | 1 | 0 | 1 |
| 2021 | 0 | 1 | 1 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Fibrinogen" by people in Profiles.
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Choi S, Mazzeffi MA, Henderson R, Mondal S, Morita Y, Deshpande S, Tanaka KA. The FIBTEM paradox: Do coronary artery bypass grafting patients with high baseline FIBTEM clot firmness need more allogeneic blood transfusion? Transfusion. 2022 10; 62(10):2020-2028.
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Brown L, Jennings I, Kitchen S, Kitchen DP, Woods TAL, Walker ID. Pre-analytical variables in haemostasis: Findings from the United Kingdom National External Quality Assessment scheme for Blood Coagulation (UK NEQAS BC) haemolysis exercise. Int J Lab Hematol. 2021 Oct; 43(5):1198-1206.
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Graif A, Grilli CJ, Kimbiris G, Paik HH, Leung DA. Evaluation of Fibrinogen Levels during Catheter-Directed Thrombolysis for Acute Pulmonary Embolism. J Vasc Interv Radiol. 2020 08; 31(8):1281-1289.
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Kristoffersen AH, Stavelin AV, Ajzner E, Kristensen GBB, Sandberg S, Van Blerk M, Kitchen S, Kesseler D, Woods TAL, Meijer P. Pre-analytical practices for routine coagulation tests in European laboratories. A collaborative study from the European Organisation for External Quality Assurance Providers in Laboratory Medicine (EQALM). Clin Chem Lab Med. 2019 Sep 25; 57(10):1511-1521.
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Aoki M, Osaka Y, Ando K, Morita Y. Anesthesia Experience for Tonsillectomy in a Patient With Hypofibrinogenemia: A Case Report. A A Pract. 2019 Apr 15; 12(8):259-260.
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Pahys JM. Intraoperative Coagulopathy 101: Are Antifibrinolytics the Answer and How Do They Work?: Commentary on an article by Ryan P. Pong, MD, et al.: "Effect of Tranexamic Acid on Blood Loss, D-Dimer, and Fibrinogen Kinetics in Adult Spinal Deformity Surgery". J Bone Joint Surg Am. 2018 05 02; 100(9):e63.
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Tkach EK, Mackley A, Brooks A, Kessler J, Paul DA. Cryoprecipitate transfusions in the neonatal intensive care unit: a performance improvement study to decrease donor exposure. Transfusion. 2018 05; 58(5):1206-1209.
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Patounakis G, Bergh E, Forman EJ, Tao X, Lonczak A, Franasiak JM, Treff N, Scott RT. Multiple thrombophilic single nucleotide polymorphisms lack a significant effect on outcomes in fresh IVF cycles: an analysis of 1717 patients. J Assist Reprod Genet. 2016 Jan; 33(1):67-73.
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Nielsen VG, Lemole GM, Matika RW, Weinand ME, Hussaini S, Baaj AA, Steinbrenner EB. Brain tumors enhance plasmatic coagulation: the role of hemeoxygenase-1. Anesth Analg. 2014 May; 118(5):919-24.
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Thom SR, Bhopale VM, Milovanova TN, Yang M, Bogush M, Buerk DG. Nitric-oxide synthase-2 linkage to focal adhesion kinase in neutrophils influences enzyme activity and ?2 integrin function. J Biol Chem. 2013 Feb 15; 288(7):4810-8.