Synaptophysin

"Synaptophysin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A MARVEL domain-containing protein found in the presynaptic vesicles of NEURONS and NEUROENDOCRINE CELLS. It is commonly used as an immunocytochemical marker for neuroendocrine differentiation.

Descriptor ID	D016708
MeSH Number(s)	D12.776.543.488.875 D12.776.543.990.840 D12.776.631.800 D23.101.140.800
Concept/Terms	Synaptophysin Synaptophysin p38 Membrane Protein, Synaptic Vesicle

Below are MeSH descriptors whose meaning is more general than "Synaptophysin".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Membrane Proteins [D12.776.543]
MARVEL Domain-Containing Proteins [D12.776.543.488]
Synaptophysin [D12.776.543.488.875]
Vesicular Transport Proteins [D12.776.543.990]
Synaptophysin [D12.776.543.990.840]
Nerve Tissue Proteins [D12.776.631]
Synaptophysin [D12.776.631.800]
Biological Factors [D23]
Biomarkers [D23.101]
Biomarkers, Tumor [D23.101.140]
Synaptophysin [D23.101.140.800]

Below are MeSH descriptors whose meaning is related to "Synaptophysin".

Below are MeSH descriptors whose meaning is more specific than "Synaptophysin".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Synaptophysin" by people in this website by year, and whether "Synaptophysin" was a major or minor topic of these publications.

Bar chart showing 10 publications over 10 distinct years, with a maximum of 1 publications in 2004 and 2007 and 2008 and 2010 and 2011 and 2012 and 2015 and 2016 and 2018 and 2021

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2004	1	0	1
2007	1	0	1
2008	0	1	1
2010	0	1	1
2011	0	1	1
2012	1	0	1
2015	0	1	1
2016	0	1	1
2018	0	1	1
2021	0	1	1

Below are the most recent publications written about "Synaptophysin" by people in Profiles.

Qu S, Fetsch P, Thomas A, Pommier Y, Schrump DS, Miettinen MM, Chen H. Molecular Subtypes of Primary SCLC Tumors and Their Associations With Neuroendocrine and Therapeutic Markers. J Thorac Oncol. 2022 01; 17(1):141-153.

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Rauch C, Feifel E, Kern G, Murphy C, Meier F, Parson W, Beilmann M, Jennings P, Gstraunthaler G, Wilmes A. Differentiation of human iPSCs into functional podocytes. PLoS One. 2018; 13(9):e0203869.

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Sen A, Hongpaisan J, Wang D, Nelson TJ, Alkon DL. Protein Kinase C? (PKC?) Promotes Synaptogenesis through Membrane Accumulation of the Postsynaptic Density Protein PSD-95. J Biol Chem. 2016 08 05; 291(32):16462-76.

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Egbujo CN, Sinclair D, Borgmann-Winter KE, Arnold SE, Turetsky BI, Hahn CG. Molecular evidence for decreased synaptic efficacy in the postmortem olfactory bulb of individuals with schizophrenia. Schizophr Res. 2015 Oct; 168(1-2):554-62.

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Lippa CF, Rosso AL. Loss of synaptophysin immunoexpression in primary progressive aphasia. Am J Alzheimers Dis Other Demen. 2012 Jun; 27(4):250-3.

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Knoepp SM, Hookim K, Placido J, Fields KL, Roh MH. The application of immunocytochemistry to cytologic direct smears of metastatic merkel cell carcinoma. Diagn Cytopathol. 2013 Aug; 41(8):729-33.

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Griffin GD, Ferri-Kolwicz SL, Reyes BA, Van Bockstaele EJ, Flanagan-Cato LM. Ovarian hormone-induced reorganization of oxytocin-labeled dendrites and synapses lateral to the hypothalamic ventromedial nucleus in female rats. J Comp Neurol. 2010 Nov 15; 518(22):4531-45.

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Khanna P, Paidas CN, Gilbert-Barness E. Alveolar soft part sarcoma: clinical, histopathological, molecular, and ultrastructural aspects. Fetal Pediatr Pathol. 2008; 27(1):31-40.

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Haleem K, Lippa CF, Smith TW, Kowa H, Wu J, Iwatsubo T. Presenilin-1 C410Y Alzheimer disease plaques contain synaptic proteins. Am J Alzheimers Dis Other Demen. 2007 Apr-May; 22(2):137-44.

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Lippa CF. Synaptophysin immunoreactivity in Pick's disease: comparison with Alzheimer's disease and dementia with Lewy bodies. Am J Alzheimers Dis Other Demen. 2004 Nov-Dec; 19(6):341-4.

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