Synaptophysin

"Synaptophysin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A MARVEL domain-containing protein found in the presynaptic vesicles of NEURONS and NEUROENDOCRINE CELLS. It is commonly used as an immunocytochemical marker for neuroendocrine differentiation.

Descriptor ID	D016708
MeSH Number(s)	D12.776.543.488.875 D12.776.543.990.840 D12.776.631.800 D23.101.140.800
Concept/Terms	Synaptophysin Synaptophysin p38 Membrane Protein, Synaptic Vesicle

Below are MeSH descriptors whose meaning is more general than "Synaptophysin".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Membrane Proteins [D12.776.543]
MARVEL Domain-Containing Proteins [D12.776.543.488]
Synaptophysin [D12.776.543.488.875]
Vesicular Transport Proteins [D12.776.543.990]
Synaptophysin [D12.776.543.990.840]
Nerve Tissue Proteins [D12.776.631]
Synaptophysin [D12.776.631.800]
Biological Factors [D23]
Biomarkers [D23.101]
Biomarkers, Tumor [D23.101.140]
Synaptophysin [D23.101.140.800]

Below are MeSH descriptors whose meaning is related to "Synaptophysin".

Below are MeSH descriptors whose meaning is more specific than "Synaptophysin".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Synaptophysin" by people in this website by year, and whether "Synaptophysin" was a major or minor topic of these publications.

Bar chart showing 19 publications over 17 distinct years, with a maximum of 2 publications in 1998 and 2015

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1998	0	2	2
1999	1	0	1
2000	0	1	1
2003	0	1	1
2004	1	0	1
2007	1	0	1
2008	0	1	1
2009	0	1	1
2010	0	1	1
2011	0	1	1
2012	1	0	1
2015	0	2	2
2016	0	1	1
2018	0	1	1
2019	0	1	1
2021	0	1	1
2024	0	1	1

Below are the most recent publications written about "Synaptophysin" by people in Profiles.

Naranjo NM, Kennedy A, Testa A, Verrillo CE, Altieri AD, Kean R, Hooper DC, Yu J, Zhao J, Abinader O, Pickles MW, Hawkins A, Kelly WK, Mitra R, Languino LR. Neuroendocrine gene subsets are uniquely dysregulated in prostate adenocarcinoma. Cancer Biol Ther. 2024 Dec 31; 25(1):2364433.

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Qu S, Fetsch P, Thomas A, Pommier Y, Schrump DS, Miettinen MM, Chen H. Molecular Subtypes of Primary SCLC Tumors and Their Associations With Neuroendocrine and Therapeutic Markers. J Thorac Oncol. 2022 01; 17(1):141-153.

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Gaur K, Gupta RK, Saran RK, Sharma MC. Composite pleomorphic xanthoastrocytoma-ganglioglioma; assessing and addressing the dilemma of differential expression of neuronal markers: Case report with diagnostic perspective. Indian J Pathol Microbiol. 2019 Apr-Jun; 62(2):296-299.

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Rauch C, Feifel E, Kern G, Murphy C, Meier F, Parson W, Beilmann M, Jennings P, Gstraunthaler G, Wilmes A. Differentiation of human iPSCs into functional podocytes. PLoS One. 2018; 13(9):e0203869.

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Sen A, Hongpaisan J, Wang D, Nelson TJ, Alkon DL. Protein Kinase C? (PKC?) Promotes Synaptogenesis through Membrane Accumulation of the Postsynaptic Density Protein PSD-95. J Biol Chem. 2016 08 05; 291(32):16462-76.

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Egbujo CN, Sinclair D, Borgmann-Winter KE, Arnold SE, Turetsky BI, Hahn CG. Molecular evidence for decreased synaptic efficacy in the postmortem olfactory bulb of individuals with schizophrenia. Schizophr Res. 2015 Oct; 168(1-2):554-62.

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Gupta RK, Saran RK, Debnath PR, Chadha R. Is histopathology informative for further characterization of DOTANOC-proven islet cell lesions in infancy? Indian J Pathol Microbiol. 2015 Jul-Sep; 58(3):410-2.

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Lippa CF, Rosso AL. Loss of synaptophysin immunoexpression in primary progressive aphasia. Am J Alzheimers Dis Other Demen. 2012 Jun; 27(4):250-3.

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Knoepp SM, Hookim K, Placido J, Fields KL, Roh MH. The application of immunocytochemistry to cytologic direct smears of metastatic merkel cell carcinoma. Diagn Cytopathol. 2013 Aug; 41(8):729-33.

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Griffin GD, Ferri-Kolwicz SL, Reyes BA, Van Bockstaele EJ, Flanagan-Cato LM. Ovarian hormone-induced reorganization of oxytocin-labeled dendrites and synapses lateral to the hypothalamic ventromedial nucleus in female rats. J Comp Neurol. 2010 Nov 15; 518(22):4531-45.

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