Mechanotransduction, Cellular
"Mechanotransduction, Cellular" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The process by which cells convert mechanical stimuli into a chemical response. It can occur in both cells specialized for sensing mechanical cues such as MECHANORECEPTORS, and in parenchymal cells whose primary function is not mechanosensory.
Descriptor ID |
D040542
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MeSH Number(s) |
G01.154.090.500 G02.111.820.580 G04.835.580
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Concept/Terms |
Mechanotransduction, Cellular- Mechanotransduction, Cellular
- Signal Transduction, Mechanical
- Mechanical Signal Transduction
- Cellular Mechanotransduction
- Mechanosensory Transduction
- Transduction, Mechanosensory
|
Below are MeSH descriptors whose meaning is more general than "Mechanotransduction, Cellular".
Below are MeSH descriptors whose meaning is more specific than "Mechanotransduction, Cellular".
This graph shows the total number of publications written about "Mechanotransduction, Cellular" by people in this website by year, and whether "Mechanotransduction, Cellular" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2002 | 0 | 1 | 1 |
2003 | 2 | 0 | 2 |
2004 | 1 | 0 | 1 |
2005 | 1 | 0 | 1 |
2006 | 1 | 0 | 1 |
2008 | 1 | 1 | 2 |
2014 | 1 | 0 | 1 |
2015 | 1 | 0 | 1 |
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Below are the most recent publications written about "Mechanotransduction, Cellular" by people in Profiles.
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Mohieldin AM, Haymour HS, Lo ST, AbouAlaiwi WA, Atkinson KF, Ward CJ, Gao M, Wessely O, Nauli SM. Protein composition and movements of membrane swellings associated with primary cilia. Cell Mol Life Sci. 2015 Jun; 72(12):2415-29.
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Noble PB, Pascoe CD, Lan B, Ito S, Kistemaker LE, Tatler AL, Pera T, Brook BS, Gosens R, West AR. Airway smooth muscle in asthma: linking contraction and mechanotransduction to disease pathogenesis and remodelling. Pulm Pharmacol Ther. 2014 Dec; 29(2):96-107.
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Goldfinger LE, Tzima E, Stockton R, Kiosses WB, Kinbara K, Tkachenko E, Gutierrez E, Groisman A, Nguyen P, Chien S, Ginsberg MH. Localized alpha4 integrin phosphorylation directs shear stress-induced endothelial cell alignment. Circ Res. 2008 Jul 18; 103(2):177-85.
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Baker AB, Ettenson DS, Jonas M, Nugent MA, Iozzo RV, Edelman ER. Endothelial cells provide feedback control for vascular remodeling through a mechanosensitive autocrine TGF-beta signaling pathway. Circ Res. 2008 Aug 1; 103(3):289-97.
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Sawakami K, Robling AG, Ai M, Pitner ND, Liu D, Warden SJ, Li J, Maye P, Rowe DW, Duncan RL, Warman ML, Turner CH. The Wnt co-receptor LRP5 is essential for skeletal mechanotransduction but not for the anabolic bone response to parathyroid hormone treatment. J Biol Chem. 2006 Aug 18; 281(33):23698-711.
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Zhou D, Herrick DJ, Rosenbloom J, Chaqour B. Cyr61 mediates the expression of VEGF, alphav-integrin, and alpha-actin genes through cytoskeletally based mechanotransduction mechanisms in bladder smooth muscle cells. J Appl Physiol (1985). 2005 Jun; 98(6):2344-54.
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Genetos DC, Geist DJ, Liu D, Donahue HJ, Duncan RL. Fluid shear-induced ATP secretion mediates prostaglandin release in MC3T3-E1 osteoblasts. J Bone Miner Res. 2005 Jan; 20(1):41-9.
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Chen NX, Geist DJ, Genetos DC, Pavalko FM, Duncan RL. Fluid shear-induced NFkappaB translocation in osteoblasts is mediated by intracellular calcium release. Bone. 2003 Sep; 33(3):399-410.
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Tanaka SM, Li J, Duncan RL, Yokota H, Burr DB, Turner CH. Effects of broad frequency vibration on cultured osteoblasts. J Biomech. 2003 Jan; 36(1):73-80.
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Kauffman KJ, Pridgen EM, Doyle FJ, Dhurjati PS, Robinson AS. Decreased protein expression and intermittent recoveries in BiP levels result from cellular stress during heterologous protein expression in Saccharomyces cerevisiae. Biotechnol Prog. 2002 Sep-Oct; 18(5):942-50.