Mechanotransduction, Cellular

"Mechanotransduction, Cellular" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The process by which cells convert mechanical stimuli into a chemical response. It can occur in both cells specialized for sensing mechanical cues such as MECHANORECEPTORS, and in parenchymal cells whose primary function is not mechanosensory.

Descriptor ID	D040542
MeSH Number(s)	G01.154.090.500 G02.111.820.580 G04.835.580
Concept/Terms	Mechanotransduction, Cellular Mechanotransduction, Cellular Signal Transduction, Mechanical Mechanical Signal Transduction Cellular Mechanotransduction Mechanosensory Transduction Transduction, Mechanosensory

Below are MeSH descriptors whose meaning is more general than "Mechanotransduction, Cellular".

Biological Sciences [G]
Physical Phenomena [G01]
Biophysical Phenomena [G01.154]
Biomechanical Phenomena [G01.154.090]
Mechanotransduction, Cellular [G01.154.090.500]
Chemical Phenomena [G02]
Biochemical Phenomena [G02.111]
Signal Transduction [G02.111.820]
Mechanotransduction, Cellular [G02.111.820.580]
Cell Physiological Phenomena [G04]
Signal Transduction [G04.835]
Mechanotransduction, Cellular [G04.835.580]

Below are MeSH descriptors whose meaning is related to "Mechanotransduction, Cellular".

Below are MeSH descriptors whose meaning is more specific than "Mechanotransduction, Cellular".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Mechanotransduction, Cellular" by people in this website by year, and whether "Mechanotransduction, Cellular" was a major or minor topic of these publications.

Bar chart showing 27 publications over 18 distinct years, with a maximum of 3 publications in 2019

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2002	0	1	1
2003	2	0	2
2004	1	0	1
2005	1	0	1
2006	1	0	1
2007	0	1	1
2008	1	1	2
2010	0	1	1
2012	2	0	2
2013	0	2	2
2014	1	1	2
2015	1	0	1
2016	2	0	2
2019	2	1	3
2020	1	0	1
2021	2	0	2
2022	0	1	1
2024	1	0	1

Below are the most recent publications written about "Mechanotransduction, Cellular" by people in Profiles.

Cenni V, Sabatelli P, Di Martino A, Merlini L, Antoniel M, Squarzoni S, Neri S, Santi S, Metti S, Bonaldo P, Faldini C. Collagen VI Deficiency Impairs Tendon Fibroblasts Mechanoresponse in Ullrich Congenital Muscular Dystrophy. Cells. 2024 Feb 22; 13(5).

View in: PubMed
Riaz M, Park J, Sewanan LR, Ren Y, Schwan J, Das SK, Pomianowski PT, Huang Y, Ellis MW, Luo J, Liu J, Song L, Chen IP, Qiu C, Yazawa M, Tellides G, Hwa J, Young LH, Yang L, Marboe CC, Jacoby DL, Campbell SG, Qyang Y. Muscle LIM Protein Force-Sensing Mediates Sarcomeric Biomechanical Signaling in Human Familial Hypertrophic Cardiomyopathy. Circulation. 2022 04 19; 145(16):1238-1253.

View in: PubMed
Barrick SK, Greenberg MJ. Cardiac myosin contraction and mechanotransduction in health and disease. J Biol Chem. 2021 11; 297(5):101297.

View in: PubMed
Pathak P, Blech-Hermoni Y, Subedi K, Mpamugo J, Obeng-Nyarko C, Ohman R, Molloy I, Kates M, Hale J, Stauffer S, Sharan SK, Mankodi A. Myopathy associated LDB3 mutation causes Z-disc disassembly and protein aggregation through PKCa and TSC2-mTOR downregulation. Commun Biol. 2021 03 19; 4(1):355.

View in: PubMed
Zhao G, Kim EW, Jiang J, Bhoot C, Charles KR, Baek J, Mohan S, Adams JS, Tetradis S, Lyons KM. CCN1/Cyr61 Is Required in Osteoblasts for Responsiveness to the Anabolic Activity of PTH. J Bone Miner Res. 2020 11; 35(11):2289-2300.

View in: PubMed
Wagner K, Girardo S, Goswami R, Rosso G, Ulbricht E, M?ller P, Soteriou D, Tr?ber N, Guck J. Colloidal crystals of compliant microgel beads to study cell migration and mechanosensitivity in 3D. Soft Matter. 2019 Dec 04; 15(47):9776-9787.

View in: PubMed
Assoian RK, Bade ND, Cameron CV, Stebe KJ. Cellular sensing of micron-scale curvature: a frontier in understanding the microenvironment. Open Biol. 2019 10 31; 9(10):190155.

View in: PubMed
Taubenberger AV, Girardo S, Tr?ber N, Fischer-Friedrich E, Kr?ter M, Wagner K, Kurth T, Richter I, Haller B, Binner M, Hahn D, Freudenberg U, Werner C, Guck J. 3D Microenvironment Stiffness Regulates Tumor Spheroid Growth and Mechanics via p21 and ROCK. Adv Biosyst. 2019 09; 3(9):e1900128.

View in: PubMed
Syeda R, Florendo MN, Cox CD, Kefauver JM, Santos JS, Martinac B, Patapoutian A. Piezo1 Channels Are Inherently Mechanosensitive. Cell Rep. 2016 11 08; 17(7):1739-1746.

View in: PubMed
Greenberg MJ, Arpag G, T?zel E, Ostap EM. A Perspective on the Role of Myosins as Mechanosensors. Biophys J. 2016 Jun 21; 110(12):2568-2576.

View in: PubMed

People

Explore

Similar Concepts

Top Journals

The Thomas Jefferson University web site, its contents and programs, is provided for informational and educational purposes only and is not intended as medical advice nor is it intended to create any physician-patient relationship. Please remember that this information should not substitute for a visit or a consultation with a health care provider. The views or opinions expressed in the resources provided do not necessarily reflect those of Thomas Jefferson University, Thomas Jefferson University Hospital, or the Jefferson Health System or staff.
Please read our Privacy Statement