STAT Transcription Factors

"STAT Transcription Factors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A family of transcription factors containing SH2 DOMAINS that are involved in CYTOKINE-mediated SIGNAL TRANSDUCTION. STAT transcription factors are recruited to the cytoplasmic region of CELL SURFACE RECEPTORS and are activated via PHOSPHORYLATION. Once activated they dimerize and translocate into the CELL NUCLEUS where they influence GENE expression. They play a role in regulating CELL GROWTH PROCESSES and CELL DIFFERENTIATION. STAT transcription factors are inhibited by SUPPRESSOR OF CYTOKINE SIGNALING PROTEINS and PROTEIN INHIBITORS OF ACTIVATED STAT.

Descriptor ID	D050791
MeSH Number(s)	D12.644.360.024.342 D12.776.157.057.186 D12.776.476.024.430 D12.776.930.840
Concept/Terms	STAT Transcription Factors STAT Transcription Factors Transcription Factors, STAT STAT (Signal Transducers and Activators of Transcription) Proteins

Below are MeSH descriptors whose meaning is more general than "STAT Transcription Factors".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Intracellular Signaling Peptides and Proteins [D12.644.360]
Adaptor Proteins, Signal Transducing [D12.644.360.024]
STAT Transcription Factors [D12.644.360.024.342]
Proteins [D12.776]
Carrier Proteins [D12.776.157]
Adaptor Proteins, Signal Transducing [D12.776.157.057]
STAT Transcription Factors [D12.776.157.057.186]
Intracellular Signaling Peptides and Proteins [D12.776.476]
Adaptor Proteins, Signal Transducing [D12.776.476.024]
STAT Transcription Factors [D12.776.476.024.430]
Transcription Factors [D12.776.930]
STAT Transcription Factors [D12.776.930.840]

Below are MeSH descriptors whose meaning is related to "STAT Transcription Factors".

Below are MeSH descriptors whose meaning is more specific than "STAT Transcription Factors".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "STAT Transcription Factors" by people in this website by year, and whether "STAT Transcription Factors" was a major or minor topic of these publications.

Bar chart showing 5 publications over 5 distinct years, with a maximum of 1 publications in 2006 and 2009 and 2014 and 2015 and 2021

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2006	0	1	1
2009	0	1	1
2014	0	1	1
2015	1	0	1
2021	0	1	1

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