Kruppel-Like Transcription Factors

"Kruppel-Like Transcription Factors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A family of zinc finger transcription factors that share homology with Kruppel protein, Drosophila. They contain a highly conserved seven amino acid spacer sequence in between their ZINC FINGER MOTIFS.

Descriptor ID	D051741
MeSH Number(s)	D12.776.260.522 D12.776.930.375
Concept/Terms	Kruppel-Like Transcription Factors Kruppel-Like Transcription Factors Kruppel Like Transcription Factors Transcription Factors, Kruppel-Like Kruppel-Like Factors Kruppel Like Factors

Below are MeSH descriptors whose meaning is more general than "Kruppel-Like Transcription Factors".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
DNA-Binding Proteins [D12.776.260]
Kruppel-Like Transcription Factors [D12.776.260.522]
Transcription Factors [D12.776.930]
Kruppel-Like Transcription Factors [D12.776.930.375]

Below are MeSH descriptors whose meaning is related to "Kruppel-Like Transcription Factors".

Below are MeSH descriptors whose meaning is more specific than "Kruppel-Like Transcription Factors".

Kruppel-Like Transcription Factors
Ikaros Transcription Factor
Kruppel-Like Factor 6
Promyelocytic Leukemia Zinc Finger Protein
Sp Transcription Factors
Zinc Finger Protein Gli3

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Kruppel-Like Transcription Factors" by people in this website by year, and whether "Kruppel-Like Transcription Factors" was a major or minor topic of these publications.

Bar chart showing 17 publications over 13 distinct years, with a maximum of 3 publications in 2000

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1995	0	1	1
2000	0	3	3
2004	0	1	1
2005	0	1	1
2006	0	2	2
2007	0	1	1
2008	0	1	1
2010	1	1	2
2011	0	1	1
2012	0	1	1
2013	0	1	1
2015	1	0	1
2017	1	0	1

Below are the most recent publications written about "Kruppel-Like Transcription Factors" by people in Profiles.

Torres A, Gubbiotti MA, Iozzo RV. Decorin-inducible Peg3 Evokes Beclin 1-mediated Autophagy and Thrombospondin 1-mediated Angiostasis. J Biol Chem. 2017 Mar 24; 292(12):5055-5069.

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Kramann R, Fleig SV, Schneider RK, Fabian SL, DiRocco DP, Maarouf O, Wongboonsin J, Ikeda Y, Heckl D, Chang SL, Rennke HG, Waikar SS, Humphreys BD. Pharmacological GLI2 inhibition prevents myofibroblast cell-cycle progression and reduces kidney fibrosis. J Clin Invest. 2015 Aug 03; 125(8):2935-51.

View in: PubMed
Ali MS, Starke RM, Jabbour PM, Tjoumakaris SI, Gonzalez LF, Rosenwasser RH, Owens GK, Koch WJ, Greig NH, Dumont AS. TNF-a induces phenotypic modulation in cerebral vascular smooth muscle cells: implications for cerebral aneurysm pathology. J Cereb Blood Flow Metab. 2013 Oct; 33(10):1564-73.

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Kim JI, Urban M, Young GD, Eto M. Reciprocal regulation controlling the expression of CPI-17, a specific inhibitor protein for the myosin light chain phosphatase in vascular smooth muscle cells. Am J Physiol Cell Physiol. 2012 Jul 1; 303(1):C58-68.

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Jacob LS, Wu X, Dodge ME, Fan CW, Kulak O, Chen B, Tang W, Wang B, Amatruda JF, Lum L. Genome-wide RNAi screen reveals disease-associated genes that are common to Hedgehog and Wnt signaling. Sci Signal. 2011 Jan 25; 4(157):ra4.

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Wu K, Jiao X, Li Z, Katiyar S, Casimiro MC, Yang W, Zhang Q, Willmarth NE, Chepelev I, Crosariol M, Wei Z, Hu J, Zhao K, Pestell RG. Cell fate determination factor Dachshund reprograms breast cancer stem cell function. J Biol Chem. 2011 Jan 21; 286(3):2132-42.

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Rodríguez E, Aburjania N, Priedigkeit NM, DiFeo A, Martignetti JA. Nucleo-cytoplasmic localization domains regulate Krüppel-like factor 6 (KLF6) protein stability and tumor suppressor function. PLoS One. 2010 Sep 09; 5(9).

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Samuels LE, Kohout J, Casanova-Ghosh E, Hagan K, Garwood P, Ferdinand F, Goldman SM. Argatroban as a primary or secondary postoperative anticoagulant in patients implanted with ventricular assist devices. Ann Thorac Surg. 2008 May; 85(5):1651-5.

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Riobo NA, Manning DR. Pathways of signal transduction employed by vertebrate Hedgehogs. Biochem J. 2007 May 1; 403(3):369-79.

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Patel JH, McMahon SB. BCL2 is a downstream effector of MIZ-1 essential for blocking c-MYC-induced apoptosis. J Biol Chem. 2007 Jan 5; 282(1):5-13.

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