Below are the most recent publications written about "Karyopherins" by people in Profiles.
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Chakravarti N, Boles A, Burzinski R, Sindaco P, Isabelle C, McConnell K, Mishra A, Porcu P. XPO1 blockade with KPT-330 promotes apoptosis in cutaneous T-cell lymphoma by activating the p53-p21 and p27 pathways. Sci Rep. 2024 04 23; 14(1):9305.
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Yang R, Ko YH, Li F, Lokareddy RK, Hou CD, Kim C, Klein S, Antol?nez S, Mar?n JF, P?rez-Segura C, Jarrold MF, Zlotnick A, Hadden-Perilla JA, Cingolani G. Structural basis for nuclear import of hepatitis B virus (HBV) nucleocapsid core. Sci Adv. 2024 Jan 12; 10(2):eadi7606.
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Doll SG, Cingolani G. Importin a/? and the tug of war to keep TDP-43 in solution: quo vadis? Bioessays. 2022 12; 44(12):e2200181.
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Florio TJ, Lokareddy RK, Yeggoni DP, Sankhala RS, Ott CA, Gillilan RE, Cingolani G. Differential recognition of canonical NF-?B dimers by Importin a3. Nat Commun. 2022 03 08; 13(1):1207.
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Attiyeh EF, Maris JM, Lock R, Reynolds CP, Kang MH, Carol H, Gorlick R, Kolb EA, Keir ST, Wu J, Landesman Y, Shacham S, Lyalin D, Kurmasheva RT, Houghton PJ, Smith MA. Pharmacodynamic and genomic markers associated with response to the XPO1/CRM1 inhibitor selinexor (KPT-330): A report from the pediatric preclinical testing program. Pediatr Blood Cancer. 2016 Feb; 63(2):276-86.
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Melo SA, Moutinho C, Ropero S, Calin GA, Rossi S, Spizzo R, Fernandez AF, Davalos V, Villanueva A, Montoya G, Yamamoto H, Schwartz S, Esteller M. A genetic defect in exportin-5 traps precursor microRNAs in the nucleus of cancer cells. Cancer Cell. 2010 Oct 19; 18(4):303-15.
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Higashi-Kovtun ME, Mosca TJ, Dickman DK, Meinertzhagen IA, Schwarz TL. Importin-beta11 regulates synaptic phosphorylated mothers against decapentaplegic, and thereby influences synaptic development and function at the Drosophila neuromuscular junction. J Neurosci. 2010 Apr 14; 30(15):5253-68.
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Debler EW, Blobel G, Hoelz A. Nuclear transport comes full circle. Nat Struct Mol Biol. 2009 May; 16(5):457-9.
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Yudin D, Hanz S, Yoo S, Iavnilovitch E, Willis D, Gradus T, Vuppalanchi D, Segal-Ruder Y, Ben-Yaakov K, Hieda M, Yoneda Y, Twiss JL, Fainzilber M. Localized regulation of axonal RanGTPase controls retrograde injury signaling in peripheral nerve. Neuron. 2008 Jul 31; 59(2):241-52.