"Immunoglobulin Idiotypes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Unique genetically-controlled determinants present on ANTIBODIES whose specificity is limited to a single group of proteins (e.g., another antibody molecule or an individual myeloma protein). The idiotype appears to represent the antigenicity of the antigen-binding site of the antibody and to be genetically codetermined with it. The idiotypic determinants have been precisely located to the IMMUNOGLOBULIN VARIABLE REGION of both immunoglobin polypeptide chains.
| Descriptor ID |
D007130
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| MeSH Number(s) |
D12.644.541.500.745 D12.776.124.486.485.680.745 D12.776.124.790.651.680.745 D12.776.377.715.548.680.745 D23.050.550.750 G02.111.570.060.425.580 G12.500.450
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| Concept/Terms |
Immunoglobulin Idiotypes- Immunoglobulin Idiotypes
- Idiotype, Immunoglobulin
- Immunoglobulin Idiotype
- Idiotypes, Immunoglobulin
|
Below are MeSH descriptors whose meaning is more general than "Immunoglobulin Idiotypes".
Below are MeSH descriptors whose meaning is more specific than "Immunoglobulin Idiotypes".
This graph shows the total number of publications written about "Immunoglobulin Idiotypes" by people in this website by year, and whether "Immunoglobulin Idiotypes" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 1 | 0 | 1 |
| 2001 | 1 | 0 | 1 |
| 2004 | 1 | 0 | 1 |
| 2005 | 0 | 1 | 1 |
| 2008 | 1 | 0 | 1 |
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Below are the most recent publications written about "Immunoglobulin Idiotypes" by people in Profiles.
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Alabyev B, Vuyyuru R, Manser T. Influence of Fas on the regulation of the response of an anti-nuclear antigen B cell clonotype to foreign antigen. Int Immunol. 2008 Oct; 20(10):1279-87.
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Wen L, Shinton SA, Hardy RR, Hayakawa K. Association of B-1 B cells with follicular dendritic cells in spleen. J Immunol. 2005 Jun 01; 174(11):6918-26.
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Dimitrijevic LA, Stojanovic M, Ciric B, Radulovic M, Stojanovic R, Popovic Z, Inic-Kanada A, Zivkovic I. Expression of Y7 cross-reactive idiotope on human IgM molecules. Immunol Invest. 2004 Feb; 33(1):1-14.
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Birebent B, Koido T, Mitchell E, Li W, Somasundaram R, Purev E, Hoey D, Mastrangelo M, Maguire H, Harris DT, Nair S, Cai E, Herlyn D. Anti-idiotypic antibody (ab2) vaccines: coupling of Ab2 BR3E4 to KLH increases humoral and/or cellular immune responses in animals and colorectal cancer patients. J Cancer Res Clin Oncol. 2001 Oct; 127 Suppl 2:R27-33.
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Vitetta ES, Tucker TF, Racila E, Huang YW, Marches R, Lane N, Scheuermann RH, Street NE, Watanabe T, Uhr JW. Tumor dormancy and cell signaling. V. Regrowth of the BCL1 tumor after dormancy is established. Blood. 1997 Jun 15; 89(12):4425-36.
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Scheuermann RH, Racila E, Uhr JW. Lyn tyrosine kinase signals cell cycle arrest in mouse and human B-cell lymphoma. Curr Top Microbiol Immunol. 1995; 194:313-21.
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Caton AJ, Herlyn D, Ross AH, Koprowski H. Identical D region sequences expressed by murine monoclonal antibodies specific for a human tumor-associated antigen. J Immunol. 1990 Mar 01; 144(5):1965-8.
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Wettendorff M, Iliopoulos D, Tempero M, Kay D, DeFreitas E, Koprowski H, Herlyn D. Idiotypic cascades in cancer patients treated with monoclonal antibody CO17-1A. Proc Natl Acad Sci U S A. 1989 May; 86(10):3787-91.
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Wettendorff M, Iliopoulos D, Schmoll E, Koprowski H, Herlyn D. Specific detection of antibodies in cancer patients following immunotherapy with anti-idiotype. J Immunol Methods. 1989 Jan 06; 116(1):105-15.
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Herlyn D, Wettendorff M, Koprowski H. Modulation of cancer patients' immune responses by anti-idiotypic antibodies. Int Rev Immunol. 1989; 4(4):347-57.