p300-CBP Transcription Factors

"p300-CBP Transcription Factors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A family of histone acetyltransferases that is structurally-related to CREB-BINDING PROTEIN and to E1A-ASSOCIATED P300 PROTEIN. They function as transcriptional coactivators by bridging between DNA-binding TRANSCRIPTION FACTORS and the basal transcription machinery. They also modify transcription factors and CHROMATIN through ACETYLATION.

Descriptor ID	D050880
MeSH Number(s)	D08.811.913.050.134.415.500.575 D12.776.930.680
Concept/Terms	p300-CBP Transcription Factors p300-CBP Transcription Factors Transcription Factors, p300-CBP p300 CBP Transcription Factors p300-CBP Coactivator Coactivator, p300-CBP p300 CBP Coactivator p300-CBP Protein p300 CBP Protein

Below are MeSH descriptors whose meaning is more general than "p300-CBP Transcription Factors".

Chemicals and Drugs [D]
Enzymes and Coenzymes [D08]
Enzymes [D08.811]
Transferases [D08.811.913]
Acyltransferases [D08.811.913.050]
Acetyltransferases [D08.811.913.050.134]
Lysine Acetyltransferases [D08.811.913.050.134.415]
Histone Acetyltransferases [D08.811.913.050.134.415.500]
p300-CBP Transcription Factors [D08.811.913.050.134.415.500.575]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Transcription Factors [D12.776.930]
p300-CBP Transcription Factors [D12.776.930.680]

Below are MeSH descriptors whose meaning is related to "p300-CBP Transcription Factors".

Below are MeSH descriptors whose meaning is more specific than "p300-CBP Transcription Factors".

p300-CBP Transcription Factors
CREB-Binding Protein
E1A-Associated p300 Protein

publications

Timeline | Most Recent

This graph shows the total number of publications written about "p300-CBP Transcription Factors" by people in this website by year, and whether "p300-CBP Transcription Factors" was a major or minor topic of these publications.

Bar chart showing 13 publications over 8 distinct years, with a maximum of 3 publications in 2001 and 2006

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2000	0	2	2
2001	0	3	3
2004	0	1	1
2006	0	3	3
2008	0	1	1
2009	0	1	1
2012	0	1	1
2024	1	0	1

Below are the most recent publications written about "p300-CBP Transcription Factors" by people in Profiles.

Sardar S, McNair CM, Ravindranath L, Chand SN, Yuan W, Bogdan D, Welti J, Sharp A, Ryan NK, Knudsen LA, Schiewer MJ, DeArment EG, Janas T, Su XA, Butler LM, de Bono JS, Frese K, Brooks N, Pegg N, Knudsen KE, Shafi AA. AR coactivators, CBP/p300, are critical mediators of DNA repair in prostate cancer. Oncogene. 2024 Oct; 43(43):3197-3213.

View in: PubMed
del Blanco B, Garc?a-Mariscal A, Wiest DL, Hern?ndez-Munain C. Tcra enhancer activation by inducible transcription factors downstream of pre-TCR signaling. J Immunol. 2012 Apr 01; 188(7):3278-93.

View in: PubMed
Ma Y, Fan S, Hu C, Meng Q, Fuqua SA, Pestell RG, Tomita YA, Rosen EM. BRCA1 regulates acetylation and ubiquitination of estrogen receptor-alpha. Mol Endocrinol. 2010 Jan; 24(1):76-90.

View in: PubMed
Zhang XY, Varthi M, Sykes SM, Phillips C, Warzecha C, Zhu W, Wyce A, Thorne AW, Berger SL, McMahon SB. The putative cancer stem cell marker USP22 is a subunit of the human SAGA complex required for activated transcription and cell-cycle progression. Mol Cell. 2008 Jan 18; 29(1):102-11.

View in: PubMed
Fu M, Liu M, Sauve AA, Jiao X, Zhang X, Wu X, Powell MJ, Yang T, Gu W, Avantaggiati ML, Pattabiraman N, Pestell TG, Wang F, Quong AA, Wang C, Pestell RG. Hormonal control of androgen receptor function through SIRT1. Mol Cell Biol. 2006 Nov; 26(21):8122-35.

View in: PubMed
Knoepfler PS, Zhang XY, Cheng PF, Gafken PR, McMahon SB, Eisenman RN. Myc influences global chromatin structure. EMBO J. 2006 Jun 21; 25(12):2723-34.

View in: PubMed
Gong J, Zhu J, Goodman OB, Pestell RG, Schlegel PN, Nanus DM, Shen R. Activation of p300 histone acetyltransferase activity and acetylation of the androgen receptor by bombesin in prostate cancer cells. Oncogene. 2006 Mar 30; 25(14):2011-21.

View in: PubMed
Patel JH, Du Y, Ard PG, Phillips C, Carella B, Chen CJ, Rakowski C, Chatterjee C, Lieberman PM, Lane WS, Blobel GA, McMahon SB. The c-MYC oncoprotein is a substrate of the acetyltransferases hGCN5/PCAF and TIP60. Mol Cell Biol. 2004 Dec; 24(24):10826-34.

View in: PubMed
Park J, Kunjibettu S, McMahon SB, Cole MD. The ATM-related domain of TRRAP is required for histone acetyltransferase recruitment and Myc-dependent oncogenesis. Genes Dev. 2001 Jul 01; 15(13):1619-24.

View in: PubMed
Lang SE, McMahon SB, Cole MD, Hearing P. E2F transcriptional activation requires TRRAP and GCN5 cofactors. J Biol Chem. 2001 Aug 31; 276(35):32627-34.

View in: PubMed

People

Explore

Similar Concepts

Top Journals

The Thomas Jefferson University web site, its contents and programs, is provided for informational and educational purposes only and is not intended as medical advice nor is it intended to create any physician-patient relationship. Please remember that this information should not substitute for a visit or a consultation with a health care provider. The views or opinions expressed in the resources provided do not necessarily reflect those of Thomas Jefferson University, Thomas Jefferson University Hospital, or the Jefferson Health System or staff.
Please read our Privacy Statement