Cyclic AMP Receptor Protein
"Cyclic AMP Receptor Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A transcriptional regulator in prokaryotes which, when activated by binding cyclic AMP, acts at several promoters. Cyclic AMP receptor protein was originally identified as a catabolite gene activator protein. It was subsequently shown to regulate several functions unrelated to catabolism, and to be both a negative and a positive regulator of transcription. Cell surface cyclic AMP receptors are not included (CYCLIC AMP RECEPTORS), nor are the eukaryotic cytoplasmic cyclic AMP receptor proteins, which are the regulatory subunits of CYCLIC AMP-DEPENDENT PROTEIN KINASES.
| Descriptor ID |
D002373
|
| MeSH Number(s) |
D12.776.930.165
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| Concept/Terms |
Cyclic AMP Receptor Protein- Cyclic AMP Receptor Protein
- cAMP Receptor Proteins
- Proteins, cAMP Receptor
- Receptor Proteins, cAMP
- Catabolic Gene Activator
- Gene Activator, Catabolic
- Gene Activators, Catabolic
- Catabolic Gene Activators
- Cyclic AMP Receptor Proteins
- Activator Protein, Catabolite
- Activator Proteins, Catabolite
- Catabolite Activator Proteins
- Protein, Catabolite Activator
- Proteins, Catabolite Activator
- Catabolite Activator Protein
- Catabolite Gene Activator Protein
- Catabolite Gene Activator Proteins
- Catabolite Regulator Protein
- Catabolite Regulator Proteins
- Protein, Catabolite Regulator
- Proteins, Catabolite Regulator
- Regulator Protein, Catabolite
- Regulator Proteins, Catabolite
- cAMP Receptor Protein
- Protein, cAMP Receptor
- Receptor Protein, cAMP
- Activator, Catabolic Gene
- Activators, Catabolic Gene
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Below are MeSH descriptors whose meaning is more general than "Cyclic AMP Receptor Protein".
Below are MeSH descriptors whose meaning is more specific than "Cyclic AMP Receptor Protein".
This graph shows the total number of publications written about "Cyclic AMP Receptor Protein" by people in this website by year, and whether "Cyclic AMP Receptor Protein" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 2 | 0 | 2 |
| 2006 | 1 | 0 | 1 |
| 2008 | 1 | 0 | 1 |
| 2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "Cyclic AMP Receptor Protein" by people in Profiles.
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Porter JR, Moeder KE, Sibbald CA, Zimmerman MI, Hart KM, Greenberg MJ, Bowman GR. Cooperative Changes in Solvent Exposure Identify Cryptic Pockets, Switches, and Allosteric Coupling. Biophys J. 2019 03 05; 116(5):818-830.
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Ferrell E, Carty NL, Colmer-Hamood JA, Hamood AN, West SE. Regulation of Pseudomonas aeruginosa ptxR by Vfr. Microbiology. 2008 Feb; 154(Pt 2):431-9.
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Kanack KJ, Runyen-Janecky LJ, Ferrell EP, Suh SJ, West SE. Characterization of DNA-binding specificity and analysis of binding sites of the Pseudomonas aeruginosa global regulator, Vfr, a homologue of the Escherichia coli cAMP receptor protein. Microbiology. 2006 Dec; 152(Pt 12):3485-96.
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Dasgupta N, Ferrell EP, Kanack KJ, West SE, Ramphal R. fleQ, the gene encoding the major flagellar regulator of Pseudomonas aeruginosa, is sigma70 dependent and is downregulated by Vfr, a homolog of Escherichia coli cyclic AMP receptor protein. J Bacteriol. 2002 Oct; 184(19):5240-50.
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Suh SJ, Runyen-Janecky LJ, Maleniak TC, Hager P, MacGregor CH, Zielinski-Mozny NA, Phibbs PV, West SE. Effect of vfr mutation on global gene expression and catabolite repression control of Pseudomonas aeruginosa. Microbiology. 2002 May; 148(Pt 5):1561-9.