"Stathmin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A ubiquitous phosphoprotein that serves as an intracellular substrate for a variety of SIGNAL TRANSDUCTION PATHWAYS. PHOSPHORYLATION of stathmin occurs during CELL CYCLE progression, and stathmin functions as a microtubule-destabilizing protein that promotes MICROTUBULE depolymerization during INTERPHASE and late MITOSIS. Stathmin is expressed at very high levels in a variety of human CANCERS.
| Descriptor ID |
D050777
|
| MeSH Number(s) |
D12.776.220.600.450.480 D12.776.624.664.700.957 D12.776.744.772
|
| Concept/Terms |
Stathmin- Stathmin
- Leukemia-Associated Phosphoprotein p18
- Leukemia Associated Phosphoprotein p18
- p18, Leukemia-Associated Phosphoprotein
- Metablastin
- Prosolin
- Op18 Phosphoprotein
- Phosphoprotein, Op18
- Phosphoprotein p18
- p18, Phosphoprotein
- Phosphoprotein p19
- p19, Phosphoprotein
- Lap18 Protein
- Oncoprotein 18
|
Below are MeSH descriptors whose meaning is more general than "Stathmin".
Below are MeSH descriptors whose meaning is more specific than "Stathmin".
This graph shows the total number of publications written about "Stathmin" by people in this website by year, and whether "Stathmin" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 0 | 1 | 1 |
| 2011 | 1 | 0 | 1 |
| 2016 | 0 | 1 | 1 |
| 2017 | 1 | 0 | 1 |
| 2019 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Stathmin" by people in Profiles.
-
Currier AW, Kolb EA, Gorlick RG, Roth ME, Gopalakrishnan V, Sampson VB. p27/Kip1 functions as a tumor suppressor and oncoprotein in osteosarcoma. Sci Rep. 2019 04 16; 9(1):6161.
-
Vetter NS, Kolb EA, Mills CC, Sampson VB. The Microtubule Network and Cell Death Are Regulated by an miR-34a/Stathmin 1/?III-Tubulin Axis. Mol Cancer Res. 2017 07; 15(7):953-964.
-
Sampson VB, Vetter NS, Zhang W, Patil PU, Mason RW, George E, Gorlick R, Kolb EA. Integrating mechanisms of response and resistance against the tubulin binding agent Eribulin in preclinical models of osteosarcoma. Oncotarget. 2016 Dec 27; 7(52):86594-86607.
-
Wosnitzer MS, Domingo-Domenech J, Castillo-Martin M, Ritch C, Mansukhani M, Petrylack DP, Benson MC, McKiernan JM, Cordon-Cardo C. Predictive value of microtubule associated proteins tau and stathmin in patients with nonmuscle invasive bladder cancer receiving adjuvant intravesical taxane therapy. J Urol. 2011 Nov; 186(5):2094-100.
-
Baldassarre G, Belletti B, Nicoloso MS, Schiappacassi M, Vecchione A, Spessotto P, Morrione A, Canzonieri V, Colombatti A. p27(Kip1)-stathmin interaction influences sarcoma cell migration and invasion. Cancer Cell. 2005 Jan; 7(1):51-63.