CDX2 Transcription Factor
"CDX2 Transcription Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An antennapedia-like homeodomain transcription factor that regulates the expression of multiple genes in the INTESTINAL MUCOSA. It plays a critical role in many processes from early differentiation to maintenance of the intestinal epithelial lining of both the small and large intestine.
| Descriptor ID |
D000071616
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| MeSH Number(s) |
D12.776.260.400.140 D12.776.660.201 D12.776.930.146
|
| Concept/Terms |
CDX2 Transcription Factor- CDX2 Transcription Factor
- Homeobox Protein CDX-2
- CDX-2, Homeobox Protein
- Homeobox Protein CDX 2
- Homeobox Protein CDX2
- CDX2, Homeobox Protein
- Caudal Type Homeo Box Transcription Factor 2
- Caudal Type Homeo Box 2 Protein
- Transcription Factor CDX2
- CDX2, Transcription Factor
- Cdx-2 Protein
- Cdx 2 Protein
- Cdx-3 Protein
- Cdx 3 Protein
- Cdx-2-3 Protein
- Cdx 2 3 Protein
- CDX2 Protein
- Caudal Type Homeobox Transcription Factor 2
|
Below are MeSH descriptors whose meaning is more general than "CDX2 Transcription Factor".
Below are MeSH descriptors whose meaning is more specific than "CDX2 Transcription Factor".
This graph shows the total number of publications written about "CDX2 Transcription Factor" by people in this website by year, and whether "CDX2 Transcription Factor" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2016 | 0 | 1 | 1 |
| 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "CDX2 Transcription Factor" by people in Profiles.
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Suzuki K, Masuike Y, Mizuno R, Sachdeva UM, Chatterji P, Andres SF, Sun W, Klein-Szanto AJ, Besharati S, Remotti HE, Verzi MP, Rustgi AK. LIN28B induces a differentiation program through CDX2 in colon cancer. JCI Insight. 2021 05 10; 6(9).
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Inaguma S, Lasota J, Wang Z, Felisiak-Golabek A, Ikeda H, Miettinen M. Clinicopathologic profile, immunophenotype, and genotype of CD274 (PD-L1)-positive colorectal carcinomas. Mod Pathol. 2017 02; 30(2):278-285.
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Watts JA, Zhang C, Klein-Szanto AJ, Kormish JD, Fu J, Zhang MQ, Zaret KS. Study of FoxA pioneer factor at silent genes reveals Rfx-repressed enhancer at Cdx2 and a potential indicator of esophageal adenocarcinoma development. PLoS Genet. 2011 Sep; 7(9):e1002277.
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Porjazova E, Zaprjanov Z, Batashki I, Markova D, Milchev N. [Immunohistochemical profile of colorectal and ovarian carcinomas--examination with cytokeratin 7, cytokeratin 20, beta catenin and cDX 2]. Akush Ginekol (Sofiia). 2009; 48(2):7-12.
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Di Guglielmo MD, Park J, Schulz S, Waldman SA. Nucleotide requirements for CDX2 binding to the cis promoter element mediating intestine-specific expression of guanylyl cyclase C. FEBS Lett. 2001 Oct 26; 507(2):128-32.
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Park J, Schulz S, Waldman SA. Intestine-specific activity of the human guanylyl cyclase C promoter is regulated by Cdx2. Gastroenterology. 2000 Jul; 119(1):89-96.