"Thyroid Nuclear Factor 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A homeobox protein and transcription factor that localizes to the cell nucleus where it activates expression of thyroid specific genes such as THYROGLOBULIN and the THYROTROPIN RECEPTOR. It is critical for maintaining thyroid tissue in a differentiated state and also plays a role in lung development. Mutations in the NKX2-1 gene are associated with CHOREA, BENIGN HEREDITARY.
| Descriptor ID |
D000074482
|
| MeSH Number(s) |
D12.776.260.400.871 D12.776.660.823 D12.776.930.888
|
| Concept/Terms |
Thyroid Nuclear Factor 1- Thyroid Nuclear Factor 1
- Thyroid Transcription Factor 1
- TITF-1 Protein
- TITF 1 Protein
- Homeobox Protein Nkx-2.1
- Homeobox Protein Nkx 2.1
- Nkx-2.1, Homeobox Protein
- NK2 Homeobox 1 Protein
- TITF1 Protein
- TTF-1 Thyroid Nuclear Factor
- TTF 1 Thyroid Nuclear Factor
- Thyroid-Specific Enhancer-Binding Protein
- Enhancer-Binding Protein, Thyroid-Specific
- Thyroid Specific Enhancer Binding Protein
|
Below are MeSH descriptors whose meaning is more general than "Thyroid Nuclear Factor 1".
Below are MeSH descriptors whose meaning is more specific than "Thyroid Nuclear Factor 1".
This graph shows the total number of publications written about "Thyroid Nuclear Factor 1" by people in this website by year, and whether "Thyroid Nuclear Factor 1" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Thyroid Nuclear Factor 1" by people in Profiles.
-
Bauer P, Kreuz FR, B?rk K, Saft C, Andrich J, Heilemann H, Riess O, Sch?ls L. Mutations in TITF1 are not relevant to sporadic and familial chorea of unknown cause. Mov Disord. 2006 Oct; 21(10):1734-7.
-
Doyle DA, Gonzalez I, Thomas B, Scavina M. Autosomal dominant transmission of congenital hypothyroidism, neonatal respiratory distress, and ataxia caused by a mutation of NKX2-1. J Pediatr. 2004 Aug; 145(2):190-3.
-
Spilde TL, Bhatia AM, Miller KA, Ostlie DJ, Chaignaud BE, Holcomb GW, Snyder CL, Gittes GK. Thyroid transcription factor-1 expression in the human neonatal tracheoesophageal fistula. J Pediatr Surg. 2002 Jul; 37(7):1065-7.