NF-kappa B

"NF-kappa B" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Ubiquitous, inducible, nuclear transcriptional activator that binds to enhancer elements in many different cell types and is activated by pathogenic stimuli. The NF-kappa B complex is a heterodimer composed of two DNA-binding subunits: NF-kappa B1 and relA.

Descriptor ID	D016328
MeSH Number(s)	D12.776.260.600 D12.776.660.600 D12.776.930.600
Concept/Terms	NF-kappa B NF-kappa B kappa B Enhancer Binding Protein NF-kappaB NF kappaB Transcription Factor NF-kB Factor NF-kB, Transcription NF-kB, Transcription Factor Transcription Factor NF kB NF-kB NF kB Immunoglobulin Enhancer-Binding Protein Enhancer-Binding Protein, Immunoglobulin Immunoglobulin Enhancer Binding Protein Nuclear Factor kappa B Ig-EBP-1 Ig-EBP-1 Ig EBP 1

Below are MeSH descriptors whose meaning is more general than "NF-kappa B".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
DNA-Binding Proteins [D12.776.260]
NF-kappa B [D12.776.260.600]
Nuclear Proteins [D12.776.660]
NF-kappa B [D12.776.660.600]
Transcription Factors [D12.776.930]
NF-kappa B [D12.776.930.600]

Below are MeSH descriptors whose meaning is related to "NF-kappa B".

Below are MeSH descriptors whose meaning is more specific than "NF-kappa B".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "NF-kappa B" by people in this website by year, and whether "NF-kappa B" was a major or minor topic of these publications.

Bar chart showing 168 publications over 24 distinct years, with a maximum of 18 publications in 2002

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1998	1	0	1
1999	3	0	3
2000	2	0	2
2001	3	1	4
2002	7	11	18
2003	6	4	10
2004	6	5	11
2005	7	8	15
2006	9	7	16
2007	7	10	17
2008	5	5	10
2009	6	6	12
2010	4	4	8
2011	5	3	8
2012	1	4	5
2013	2	1	3
2014	1	2	3
2015	1	7	8
2016	1	2	3
2017	1	3	4
2020	0	1	1
2021	0	1	1
2022	3	0	3
2024	1	1	2

Below are the most recent publications written about "NF-kappa B" by people in Profiles.

Guo ZF, Tongmuang N, Li C, Zhang C, Hu L, Capreri D, Zuo MX, Summer R, Sun J. Inhibiting endothelial cell Mst1 attenuates acute lung injury in mice. JCI Insight. 2024 Sep 10; 9(17).

View in: PubMed
Anilkumar S, Wright-Jin E. NF-?B as an Inducible Regulator of Inflammation in the Central Nervous System. Cells. 2024 Mar 11; 13(6).

View in: PubMed
Merline R, R?dig H, Zeng-Brouwers J, Poluzzi C, Tascher G, Michaelis J, Lopez-Mosqueda J, Rhiner A, Huber LS, Diehl V, Dikic I, K?gel D, M?nch C, Wygrecka M, Schaefer L. A20 binding and inhibitor of nuclear factor kappa B (NF-?B)-1 (ABIN-1): a novel modulator of mitochondrial autophagy. Am J Physiol Cell Physiol. 2023 02 01; 324(2):C339-C352.

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Wang V, Heffer A, Roztocil E, Feldon SE, Libby RT, Woeller CF, Kuriyan AE. TNF-a and NF-?B signaling play a critical role in cigarette smoke-induced epithelial-mesenchymal transition of retinal pigment epithelial cells in proliferative vitreoretinopathy. PLoS One. 2022; 17(9):e0271950.

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Florio TJ, Lokareddy RK, Yeggoni DP, Sankhala RS, Ott CA, Gillilan RE, Cingolani G. Differential recognition of canonical NF-?B dimers by Importin a3. Nat Commun. 2022 03 08; 13(1):1207.

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Vazquez C, Swanson SE, Negatu SG, Dittmar M, Miller J, Ramage HR, Cherry S, Jurado KA. SARS-CoV-2 viral proteins NSP1 and NSP13 inhibit interferon activation through distinct mechanisms. PLoS One. 2021; 16(6):e0253089.

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Shenoda BB, Ramanathan S, Gupta R, Tian Y, Jean-Toussaint R, Alexander GM, Addya S, Somarowthu S, Sacan A, Ajit SK. Xist attenuates acute inflammatory response by female cells. Cell Mol Life Sci. 2021 Jan; 78(1):299-316.

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Wilde L, Roche M, Domingo-Vidal M, Tanson K, Philp N, Curry J, Martinez-Outschoorn U. Metabolic coupling and the Reverse Warburg Effect in cancer: Implications for novel biomarker and anticancer agent development. Semin Oncol. 2017 06; 44(3):198-203.

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Lu S, Ge M, Zheng Y, Li J, Feng X, Feng S, Huang J, Feng Y, Yang D, Shi J, Chen F, Han Z. CD106 is a novel mediator of bone marrow mesenchymal stem cells via NF-?B in the bone marrow failure of acquired aplastic anemia. Stem Cell Res Ther. 2017 Aug 01; 8(1):178.

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Brescia AC, Simonds MM, Sullivan KE, Rose CD. Secretion of pro-inflammatory cytokines and chemokines and loss of regulatory signals by fibroblast-like synoviocytes in juvenile idiopathic arthritis. Proteomics Clin Appl. 2017 05; 11(5-6).

View in: PubMed

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