Tumor Protein p73

"Tumor Protein p73" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A homolog of p53 TUMOR SUPPRESSOR PROTEIN that encodes full-length trans-activating and N-terminally-truncated (DeltaN) isoforms. Detection of splice variants and isoforms in the nervous system (human TELENCEPHALON, CHOROID PLEXUS; CEREBROSPINAL FLUID), embryonic tissue, human BREAST CANCER; OVARIAN CANCER, suggest roles in cellular differentiation.

Descriptor ID	D000072160
MeSH Number(s)	D12.776.260.885 D12.776.624.776.820 D12.776.660.912 D12.776.930.969
Concept/Terms	Tumor Protein p73 Tumor Protein p73 Protein p73, Tumor p73, Tumor Protein Protein p73 p73, Protein p73 Protein Protein, p73 Tumor Suppressor Protein p73 Tap73 Protein, Human Human Tap73 Protein Protein, Human Tap73 p73-alpha p73-alpha p73 alpha p73-beta p73-beta p73 beta TP73 Protein TP73 Protein Protein, TP73

Below are MeSH descriptors whose meaning is more general than "Tumor Protein p73".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
DNA-Binding Proteins [D12.776.260]
Tumor Protein p73 [D12.776.260.885]
Neoplasm Proteins [D12.776.624]
Tumor Suppressor Proteins [D12.776.624.776]
Tumor Protein p73 [D12.776.624.776.820]
Nuclear Proteins [D12.776.660]
Tumor Protein p73 [D12.776.660.912]
Transcription Factors [D12.776.930]
Tumor Protein p73 [D12.776.930.969]

Below are MeSH descriptors whose meaning is related to "Tumor Protein p73".

Below are MeSH descriptors whose meaning is more specific than "Tumor Protein p73".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Tumor Protein p73" by people in this website by year, and whether "Tumor Protein p73" was a major or minor topic of these publications.

Bar chart showing 7 publications over 7 distinct years, with a maximum of 1 publications in 2002 and 2003 and 2010 and 2011 and 2013 and 2015 and 2016

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2002	0	1	1
2003	0	1	1
2010	0	1	1
2011	0	1	1
2013	0	1	1
2015	0	1	1
2016	1	0	1

Below are the most recent publications written about "Tumor Protein p73" by people in Profiles.

Si H, Lu H, Yang X, Mattox A, Jang M, Bian Y, Sano E, Viadiu H, Yan B, Yau C, Ng S, Lee SK, Romano RA, Davis S, Walker RL, Xiao W, Sun H, Wei L, Sinha S, Benz CC, Stuart JM, Meltzer PS, Van Waes C, Chen Z. TNF-a modulates genome-wide redistribution of ?Np63a/TAp73 and NF-?B cREL interactive binding on TP53 and AP-1 motifs to promote an oncogenic gene program in squamous cancer. Oncogene. 2016 11 03; 35(44):5781-5794.

View in: PubMed
Tonsing-Carter E, Bailey BJ, Saadatzadeh MR, Ding J, Wang H, Sinn AL, Peterman KM, Spragins TK, Silver JM, Sprouse AA, Georgiadis TM, Gunter TZ, Long EC, Minto RE, Marchal CC, Batuello CN, Safa AR, Hanenberg H, Territo PR, Sandusky GE, Mayo LD, Eischen CM, Shannon HE, Pollok KE. Potentiation of Carboplatin-Mediated DNA Damage by the Mdm2 Modulator Nutlin-3a in a Humanized Orthotopic Breast-to-Lung Metastatic Model. Mol Cancer Ther. 2015 Dec; 14(12):2850-63.

View in: PubMed
Zaika E, Bhardwaj V, Wei J, Washington MK, Souza R, El-Rifai W, Zaika A. Proinflammatory cytokines and bile acids upregulate ?Np73 protein, an inhibitor of p53 and p73 tumor suppressors. PLoS One. 2013; 8(5):e64306.

View in: PubMed
D'Agostino L, Giordano A. A novel dual signaling axis for NSP 5a3a induced apoptosis in head and neck carcinoma. Oncotarget. 2011 Dec; 2(12):1055-74.

View in: PubMed
Caracciolo V, Macaluso M, D'Agostino L, Montanari M, Scheff J, Reiss K, Khalili K, Giordano A. Cross-talk between T-Ag presence and pRb family and p53/p73 signaling in mouse and human medulloblastoma. J Cell Biochem. 2010 May; 110(1):182-90.

View in: PubMed
La Sala D, Macaluso M, Trimarchi C, Giordano A, Cinti C. Triggering of p73-dependent apoptosis in osteosarcoma is under the control of E2Fs-pRb2/p130 complexes. Oncogene. 2003 Jun 05; 22(23):3518-29.

View in: PubMed
Pucci B, Claudio PP, Masciullo V, Bellincampi L, Terrinoni A, Khalili K, Melino G, Giordano A. pRb2/p130 promotes radiation-induced cell death in the glioblastoma cell line HJC12 by p73 upregulation and Bcl-2 downregulation. Oncogene. 2002 Aug 29; 21(38):5897-905.

View in: PubMed

People

Explore

Similar Concepts

Top Journals

The Thomas Jefferson University web site, its contents and programs, is provided for informational and educational purposes only and is not intended as medical advice nor is it intended to create any physician-patient relationship. Please remember that this information should not substitute for a visit or a consultation with a health care provider. The views or opinions expressed in the resources provided do not necessarily reflect those of Thomas Jefferson University, Thomas Jefferson University Hospital, or the Jefferson Health System or staff.
Please read our Privacy Statement