Inhibitor of Growth Protein 1
"Inhibitor of Growth Protein 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
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A nuclear protein and tumor suppressor that contains a C-terminal PHD ZINC FINGER. It is expressed in different isoforms in various tissues and interacts with TUMOR SUPPRESSOR PROTEIN P53 to negatively regulate cell growth. Reduced expression and chromosomal rearrangements of the ING1 gene are associated with different cancers including HEAD AND NECK NEOPLASMS.
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